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HomeMy WebLinkAboutCOM 0271.235 2012-2014 G mail - glvsophate 1 hnps:/�mail.goog]e.cornhnail/?ui=2&ik=9d3676755b&view=pt&sear... COUNTY CLERK '',' Gm * COUNTY OF HAWAI'2 '. RECEIVED pp� / Time By M ii4 Ben C. <Iivingfoodshawaii @gmail.com> r= , Dat_ _7, glysophate 1 1 message Ben C. <livingfoodshawaii @gmail.com> Sun, Jun 30, 2013 at 11:29 PM To: Tao Jones <livingfoodshawaii @gmail.com> Entropy 2013, 15(4), 1416-1463; doi:10.3390/e15041416 Review Glyphosate's Suppression of Cytochrome P450 Enzymes and Amino Acid Biosynthesis by the Gut Microbiome: Pathways to Modern Diseases Anthony Samsel 1 and Stephanie Seneff 2,* 1 Independent Scientist and Consultant, Deerfield, NH 03037, USA 2 Computer Science and Artificial Intelligence Laboratory, MIT, Cambridge, MA 02139, USA *Author to whom correspondence should be addressed. Received: 15 January 2013; in revised form: 10 April 2013/Accepted: 10 April 2013/ Published: 18 April 2013 (This article belongs to the Special Issue Biosemiotic Entropy: Disorder, Disease. and Mortality) ml Download PDF Full-Text [518 KB, uploaded 18 April 2013 14:15 CEST] Abstract: Glyphosate, the active ingredient in Roundup®, is the most popular herbicide used worldwide. The industry asserts it is minimally toxic to humans, but here we argue otherwise. Residues are found in the main foods of the Western diet, comprised primarily of sugar, corn, soy and wheat. Glyphosate's inhibition of cytochrome P450 (CYP) enzymes is an overlooked component of its toxicity to mammals. CYP enzymes play crucial roles in biology, one of which is to detoxify xenobiotics. Thus, glyphosate enhances the damaging effects of other food borne chemical residues and environmental toxins. Negative impact on the body is insidious and manifests slowly over time as inflammation damages cellular systems throughout the body. Here, we show how interference with CYP enzymes acts synergistically with disruption of the biosynthesis of aromatic amino acids by gut bacteria, as well as impairment in serum sulfate transport. Consequences are most of the diseases and conditions associated with a Western diet, which include gastrointestinal disorders, obesity, diabetes, heart disease, depression, autism, infertility, cancer and Alzheimer's disease. We explain the documented effects of glyphosate and its ability to induce disease, and we show that glyphosate is the "textbook example" of exogenous semiotic entropy: the disruption of homeostasis by environmental toxins. Comm. No. e 7 /. a3s Ref.To: P/PS M TC% Ref. Date, JUL 2 2013 I � � (,t 7/1/2013 2:55 PM Cimail -glysophate 2 https:/,email.google.com/maii/?ui=2&ik=9d3676755b&view=pt&sear... (Iri Ben C. <livingfoodshawaii@gmail.com> glysophate 2 1 message Ben C. <livingfoodshawaii @gmail.com> Sun, Jun 30, 2013 at 11:32 PM To: Tao Jones <livingfoodshawaii @gmaii.com> Glyphosate induces human breast cancer cells growth via estrogen receptors. - GreenMedinfo Summary Abstract Title: Glyphosate induces human breast cancer cells growth via estrogen receptors. Abstract Source: Food Chem Toxicol. 2013 Jun 8. Epub 2013 Jun 8. PMID: 23756170 Abstract Author(s): Siriporn Thongprakaisang, Apinya Thiantanawat, Nuchanart Rangkadilok, Tawit Suriyo, Jutamaad Satayavivad Article Affiliation: Environmental Toxicology Program, Chulabhorn Graduate Institute, Kamphaengphet 6 Road, Laksi, Bangkok 10210, Thailand. Abstract: Glyphosate is an active ingredient of the most widely used herbicide and it is believed to be less toxic than other pesticides. However, several recent studies showed its potential adverse health effects to humans as it may be an endocrine disruptor. This study focuses on the effects of pure glyphosate on estrogen receptors (ERs) mediated transcriptional activity and their expressions. Glyphosate exerted proliferative effects only in human hormone-dependent breast cancer, T47D cells, but not in hormoneindependent breast cancer, MDA-MB231 cells, at 10(-12) to 10(-6) M in estrogen withdrawal condition. The proliferative concentrations of glyphosate that induced the activation of estrogen response element (ERE) transcription activity were 5-13 fold of control in T47D-KBluc cells and this activation was inhibited by an estrogen antagonist, ICI 182780, indicating that the estrogenic activity of glyphosate was mediated via ERs. Furthermore, glyphosate also altered both ERa and I3expression. These results indicated that low and environmentally relevant concentrations of glyphosate possessed estrogenic activity. Glyphosate-based herbicides are widely used for soybean cultivation, and our results also found that there was an additive estrogenic effect between glyphosate and genistein, a phytoestrogen in soybeans. However, these additive effects of glyphosate contamination in soybeans need further animal study. Article Published Date : Jun 07, 2013 Study Type : In Vitro Study 1 of I 7/1/2013 2:56 PM Soil, Minerals, and Human Health by Benjamin Cohn I believe the main goal of agriculture is to provide nutrition. Or at least thats what i want it to be, How many people want agriculture to provide them with nutritious food? As humans we have chemical bodies that use the nutrients from our food to create trillions of chemical reactions in trillions of cells every moment. As a nutritionist, detoxification specialist, and someone who is passionate about health and healing I know that the human body needs at least 64 detectable minerals to function healthfully. Exactly how all these minerals are being used in the body is still being learned by scientists. What we do know is that many of the major minerals are used in organ, blood, bone, and tissue function. For example human blood needs iron and copper, our hearts need magnesium, our immune systems need zinc, our thyroids need iodine, and our bones and teeth need calcium, silica and over 60 other trace minerals for solid bone density. We need minerals to be strong and healthy. Where are the minerals in our bodies coming from? Minerals begin in the soil where they are absorbed by plants. The plants absorb and transform the minerals into a form that can be absorbed by humans and other animals. So even if we're eating a steak or ground beef, we are still eating an animal that ate plants. Grasses can absorb over 100 minerals in the soil. Cows that eat grass are very rarely sick. Cows that are fed grain, and especially cows that are fed GMO corn, are almost always sick. Grain fed cows are basically on antibiotic life support. Their milk utters give off a sickly puss, and their stomachs become so swollen that many have heart attacks. It is not uncommon to find masses of tumors cut out by the butcher upon slaughter. Grass fed cows are rarely payed any medical attention by ranchers. Their flesh is healthful and clean. The mineral rich grass they feed on nourishes their immune systems, organs, flesh, and bones. They fertilize the grass with their feces, and help the grass build soil. Grasses promote the growth of insects, earth worms, beneficial bacteria and mushroom mycelium in the soil. This is very important because earthworms, beneficial bacteria and mushroom mycelium hold the minerals in the soil and help make the minerals available to plants. Plants that absorb mineral rich soil thanks to mycelium, are healthy and strong without fertilizers or sprays. Our planet is a growing planet. The forests of the planet, when undisturbed by humans, literally grow topsoil. As plants grow and die and decompose they become soil. As this process happens over thousands of years, we dig down in the earth to find ancient cities that are now covered in soil because of the growth of the earth thanks to the creation of soil by plants growing and dying and becoming soil. This is a natural soil building process that requires earth worms and micro-organisms to make it all possible. Without earth worms and micro-organisms we actually see the exact opposite effect. When the micro-organisms are destroyed we lose top soil and most importantly we lose minerals that cannot be replaced by petroleum based chemical fertilizers. Petroleum based chemical fertilizers, pesticides, herbicides, and fungicides kill the micro-organisms in the soil. When the micro-organisms and mycelium die, the minerals leave as the top soil is washed away. Around the world, soil is being washed away 10 to 40 times faster than it is being replenished, destroying cropland the size of Indiana every year, according to a Cornell University study published on March 20 2006 in the Cornell Chronicle. The same study estimates the economic impact of soil erosion in the United States costs the nation about $37.6 billion each year in productivity losses. Damage from soil erosion worldwide is estimated to be $400 billion per year. Other important findings from the Cornell University study were: -As a result of erosion over the past 40 years, 30 percent of the world's arable land has become unproductive. -About 60 percent of soil that is washed away ends up in rivers. streams and lakes, making waterways more prone to flooding and to contamination from soil's fertilizers and pesticides. -Soil erosion also reduces the ability of soil to store water and support plant growth, thereby reducing its ability to support biodiversity. -Erosion promotes critical losses of water, nutrients, soil organic matter and soil biota, harming forests. rangeland and natural ecosystems. -Erosion increases the amount of dust carried by wind, which not only acts as an abrasive and air pollutant but also carries about 20 human infectious disease organisms, including anthrax and tuberculosis. This is a quote from the New York Times article "Washing Away The Fields of Iowa' published on May 4th 2011 : "According to a new report from the Environmental Working Group, Iowa's soil is washing away at rates far higher than anyone realized. For Iowa — and other Corn Belt states facing similar problems —this means an increasing loss of fertility that has to be replaced chemically. It marks a failure of stewardship, since these soils will have to feed future generations. And every particle that washes away causes problems downstream, including sedimentation —which can increase the risk of flooding —and the alarming dead zone in the Gulf of Mexico, the result of runoff of the chemical fertilizers farmers apply to make up for lost fertility. The Agriculture Department says that a "sustainable" rate of topsoil loss for most of Iowa is 5 tons per acre per year, and the actual average soil erosion is 5.2 tons. But using Iowa State University statistics and an aerial survey, the Environmental Working Group concluded that average annual soil loss in much of Iowa is double the federal government's estimates. This pace of erosion is caused partly by an increasing number of intense storms. As the report says, it has been exacerbated by a fundamental bias in federal farm policy and supports. In the dozen years before 2009, Iowa received nearly $17 billion in subsidies that fostered high-intensity farming and less than $3 billion to support conservation." The biotech industry would argue that we have to grow food this way in order to feed the world. So what are they doing vvith all the corn that is being grown in demineralized soil? They are using it to make high fructose corn syrup for soda, candy, and processed non-nutritious toxic junk food that is contributing to an increase in obesity, heart disease, diabetes, cancer, and every other disease. The rest of the corn is feeding feed lot cows that are grown in a diseased environment standing in their own feces. While grass fed cows give us nourishing beef that is mineral rich and high in omega 3, corn fed cows give us sickly nutrient deficient beef that is very low in minerals and low in omega 3. What does this mean for Hawaii? Are we willing to sacrifice our top soil, minerals, water ways, and human health for this type of agriculture? Just to give jobs to less than 1/2 of 1% of the population here in Hawaii? Alternatively there are many agricultural models that involve soil building techniques. That encourage the growth of friendly micro-organisms and mineral rich soil. With the knowledge and information we have about these methods that are already being practiced here in the islands, that were practiced by Native Hawaiians sustaining large populations for thousands of years, without imported food or imported goods, it seems outrageous that i should have to explain why conventional and GMO agriculture destroys soil and therefore destroys life. This information is not up for debate. It is widely accepted, well studied, mainstream science fact that conventional and GMO farming is toxic to our air, food, and water. As i said earlier, our bodies need mineral rich foods coming from healthy soil so that they may function properly. As long as we continue to destroy soil we destroy life, and decrease the chances of survival for ourselves, our families, our communities, and future generations. This issue is much bigger than GMO's. It question the way we've been doing agriculture in Hawaii since the sugar plantation were spraying DDT and agent orange 50 years ago that is still in our soil today. When will we wake up to science and the reality that we need healthy mineral rich soil to live and thrive. Celebrity nutritionist David Wolfe said "the future of tourism is medical tourism". We can be a model for the world and attract tourists who come here to experience health and healing in a toxin free environment where local organic fresh foods thrive and dominate the market. Where a strong healthy community is thriving and living as an example of health and healing. No matter what the testimony is of any of the pro biotech people here today-they cannot give you any science or substantial information that indicates they are building soil or creating healthful sustainable foods. They can only give you vague information that's been given to them by their employers to promote an industry that has repeatedly ignored the hundreds of independent scientific studies that find serious dangers and threats in GMO farming. If biotech were to explore the science objectively, they would have to consider the impact they have on on human life, and the very life force in the soil itself that is the source of all land based food. They will tell you GMO farming uses less pesticide, fungicide, herbicide, when the actual numbers in sales and application are much higher since the introduction of GMO plants. Pesticide, Fungicide, Herbicide, Suicide... There is no-one on the planet that knows enough about GMO plants to say with any certainty that they are safe. And anyone who looks at it objectively and researches the subject exhaustively will have to conclude that there are hundreds of scientific studies that prove GMO plants are unsafe. If GMO farming substances are as safe as the biotech lobbyists and executives would like everyone to think, than I'd like to see them spray themselves with the chemicals that are being sprayed into our land, air, food, and water. I'd like them to explain how the high fructose corn syrup from GMO corn found in soda, candy, and processed junk foods is feeding the world. I'd like them to explain why over 100,000 GMO Cotton farmers in India committed suicide. I'd like them to explain why people wear full body suits and respirators when they work in the GMO fields. I'd like them to explain why almost all the studies supporting biotech are funded by the biotech industry, while hundreds of independent published scientific studies indicate that biotech is unsafe for the natural environment, unsafe for agriculture, and especially unsafe for human consumption.