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HomeMy WebLinkAboutCOM 0271.508 2012-2014 Page 1 of 1 COUNTY CLERK Murashige, Laura COUNTY_n HAWAII From: Susan Miyasaka [sc_miyasaka @yahoo.com] 25 Sent: Monday, July 01, 2013 7:36 AM 1(113 JUL _ I ill 12: To: counciltestimony @co.hawaii.hi.us Subject: Testimony against Bill 79 draft 2 Attachments: Miyasaka-Testimony-against-Bi1179-ALL-7-1-13.pdf Dear County Council Clerk, Here is my written testimony against Bill 79, draft 2. Thank you for your attention. Best wishes, Susan C. Miyasaka Susan C. Miyasaka P.O. Box 203 Pepeekeo, HI 96783 .27/, SSOY Comm.No _. Ref.To: Ref. Date JUL 0 2 2013 7/1/2013 To: Brenda Ford, County Council Chair, Committee on Public Safety & Mass Transit Margaret Wille, Vice Chair, Committee on Public Safety & Mass Transit Karen Eoff, Member Greggor Ilagan, Member Dru Mamo Kanuha, Member Zendo Kern, Member Dennis "Fresh" Onishi, Member Valerie T. Poindexter, Member J. Yoshimoto, Member From: Susan C. Miyasaka, Ph.D. Subject: Testimony again County Council Bill No. 79, Draft No. 2 My name is Dr. Susan C. Miyasaka, and I am an Agronomist at the University of Hawaii. I am providing testimony to you as a private individual and not as a representative of the College of Tropical Agriculture and Human Resources (CTAHR). Thank you for this opportunity to provide testimony in opposition to County Council Bill No. 79 (draft 2). County Council Bill No. 79 (draft 2)proposes "to protect our agricultural heritage, our natural environment, our public health" by restricting"the further introduction and use of transgenic, genetically modified crops, plants, seed, trees, fish, livestock, and other genetic organisms in Hawai'i County." It cites the Precautionary Principle that was part of a United Nations Biosafety Protocol signed into law in 2003; however, the United States did not sign this international agreement. One definition of the Precautionary Principle (PP) is that actions should be taken to prevent damage to the environment even in cases where there is no evidence of a causal link between the technology in question and a detrimental environmental effect. In other words, the historic approach of balancing risk and benefits is replaced by a focus on risk alone (Tait and Chataway, 2010). Who can you Trust? Today, you will listen to lots of people testifying on both sides of the issues. You will need to ask yourself who can you trust? When it comes to science-based issues, you need to trust scientists who are trained in that particular area. Publication in peer-reviewed, reputable journals are considered the gold standard of scientific evidence; it means that up to 5 independent scientists have reviewed the article and found it to be worthy of publication. Also, you need to ask whether scientists or others have a conflict of interest. Are they receiving payment or other benefits from organizations on either side of the debate? I have published in peer-reviewed journals on the subject of agricultural biotechnology and I am independent of both the seed companies and anti-GMO organizations. Please vote `NO' on Bill 79, based on scientific facts: This bill is fatally flawed, because (1) the proposed ban on new genetically engineered (GE) crops lumps all GE crops together. The National Research Council (2002) organized by the National Academy of Sciences states that environmental risks of GE crops must be evaluated on a case-by-case basis. 1 Second, Bill 79 proposes a one-size-fits-all buffer zone for currently-grown GE crops. However, the distance that pollen travels depends on whether a crop is self-pollinated (such as commercial GE papaya), wind-pollinated, bee-pollinated, or not pollinated at all. Third (3), there is no credible, scientific evidence that commercial, GE crops approved by the U.S. Department of Agriculture, Food and Drug Administration, and Environmental Protection Agency are unsafe for human consumption. I have attached a list of 126 peer-reviewed studies conducted by independent scientists that demonstrated the substantial equivalence (no difference in nutritional composition) of GE crops versus non-GE crops. This list was provided by BioFortified, a non-profit organization of independent scientists dedicated to providing factual information about genetics and genetic engineering. On the Board of Directors is Dr. Pamela Ronald, professor of genetics at the University of California Davis and co-author of the book "Tomorrow's Table". http:l/www.biofortitied.org/L4enera/studies-Ibr-genera/independent- iunding/. There is a lot of misinformation being spread through anti-GMO movies, websites, and books. I have attached two fact sheets; one on food safety issues of GE crops and one on environmental issues of GE crops that summarizes scientific research. I encourage you to read them; they answer frequently asked questions about GE crops based on scientific evidence. Please vote `NO' on Bill 79 because conventional farmers and ranchers are united in opposition to Bill 79. The Hawaii Farm Bureau Federation, Hawaii Papaya Industry Association, Hawaii Export Nursery Association, Hawaii Orchid Growers' Association, Hawaii Cattlemen's Council, and Hawaii Banana Industry Association are united in opposition to Bill 79. County Council Bill 79 uses inflammatory language about commercial GE crops, that are not justified by scientific evidence. I will repeat here: there is no scientific evidence that commercialized GE crops are less safe than crops produced by conventional breeding (BioFortified web site; National Research Council, 2002; National Research Council and Institute of Medicine, 2004; Lemaux, 2008; Lemaux, 2009; Wieczorek and Wright, 2012). Passage of Bill 79 could result in the end of the papaya industry on the Big Island. In 2010, the papaya industry brought $11.1 million dollars into the state of Hawaii (HDOA and NASS, 2012). In 2008, there were over 1900 acres and 120 farms in papaya production on the Island of Hawaii. Bill 79 requires the posting of signs for GE crops; this will place a `bulls-eye' on farms that grow transgenic papaya. Already, there have been three incidences of vandalism where acres of transgenic papayas have been cut down. It is possible that the vandalism was due to anti-GMO activists, although no one has been arrested yet. htp://ww\ .biLi stand vidconc s.com/20l 2/06/12/papaya-vandals-strike-again-in-puna/ Please vote `NO' on Bill 79 because it is divisive bill. All farmers and ranchers on the Big Island need to work together to ensure food security and economic sustainability. Instead, Bill 79 seeks to pit organic farmers against conventional farmers. I was born and raised in Hawaii, and I grew up in a diverse community. We all got along, because we respected each others' cultural beliefs. 2 Please form a Task Force of farmers, ranchers, and scientists to discuss co-existence. A task force needs to be created to provide recommendations on how organic and conventional crop farmers can co-exist on the Big Island. The composition of this task force is critical to its success; it must include members who are willing to compromise. I am attaching the report of a Task Force on Co-Existence that was mandated by the Legislature of the State of Hawaii. Unfortunately, due to Task Force members who were unwilling to compromise,three reports were produced: a majority report (produced by farmers in the middle willing to compromise), and 2 minority reports (produced by farmers on both extremes who were unwilling to compromise). There is no reason that co-existence cannot happen between organic and conventional farmers. We live among one of the most culturally diverse populations in one of the most isolated areas of the globe. We can serve as a model for how co-existence can and should happen. Please vote `NO' on Bill 79. Instead, please form a Task Force to make recommendations about Co-existence of organic and conventional farmers. References: BioFortified, Inc. Studies with independent funding. http://www.biofortitied.org/genera/studies- for-genera/independent-funding/ . Accessed 27 June 2013. Hawaii Department of Agriculture and U.S.D.A. National Agricultural Statistics Service. 2012. Statistics of Hawaii Agriculture 2010. Honolulu, HI. Lemaux, P. 2008. Genetically engineered plants and foods: A scientist's analysis of the issues (Part I). Annu. Rev, Plant Biol. 59:771-812. Lemaux, P. 2009. Genetically engineered plants and foods: A Scientist's analysis of the issues (Part II). Annu. Rev. Plant Biol. 60:511-559. National Research Council. 2002. Environmental Effects of Transgenic Plants: The Scope and Adequacy of Regulation. National Academy Press, Washington, D.C. National Research Council and Institute of Medicine. 2004. Safety of Genetically Engineered Foods: Approaches to Assessing Unintended Health Effects. The National Academies Press, Washington, DC. Tait, J. and J. Chataway. 2010. Pros and Cons of the Precautionary principle (PP): European Experience with the regulation of GM Crops. http://www.genomicsnetwork.ac.uk/media/Pros%20and%20cons%20PP%20email.pdf Wieczorek, A . and M. Wright. 2012. History of Agricultural Biotechnology: How Crop Development has Evolved. Nature Education Knowledge 3(10):9. http:Pwww.nature.com/scitable/knowledgeilibrary/history-of-agricultural-biotechnology-how- crop-development-25885295 3 Studies with independent funding 1. Powell M, Wheatley AO, Omoruvi F, Asemota HN, Williams NP, Tennant PF. 2009. Comparative effects of dietary administered transgenic and conventional papaya on selected intestinal parameters in rat models. Transgenic research 19(3):511-8. 2. Batista R, Saibo N, L.ourenco T, Oliveira MM. 2008. Microarrav analyses reveal that plant mutagenesis may induce more transcriptomic changes than transgene insertion. PNAS 105(9):3640-5. (full text) 3. Bohme H, Rudloff E, Schone F, Schumann W, Hinher L, Flachowsky G. 2007.Nutritional assessment of genetically modified rapeseed synthesizing high amounts of mid-chain fatty acids including production responses of growing-finishing pigs. Archives of animal nutrition 61(4):308-16. 2007. 4. Baudo MM, Lyons R, Powers S, Pastori GM, Edwards K.1, Holdsworth MJ, Shewry PR. 206. Transgenesis has less impact on the transcriptome of wheat grain than conventional breeding. Plant biotechnology journal 4(4):369-80. 5. Brake DG, Thaler R, Evenson DP. 2004. Evaluation of Bt (Bacillus thuringiensis) corn on mouse testicular development by dual parameter flowcytometry. Journal of agricultural and food chemistry 52(7):2097-2102. 6. Brake DG, Evenson DP. 2004. A generational study of alvphosate tolerant soybeans on mouse fetal,postnatal, pubertal and adult testicular development. Food and chemical toxicology 42(1):29-36. 7. Atkinson HJ, Johnston KA, Robbins M. 2004. Prima facie evidence that a phytocystatin for transgenic plant resistance to nematodes is not a toxic risk in the human diet. Journal of Nutrition 134(2):431-434. (full text) 8. Bakan B, Melcion D, Richard-Molard D, Cahagnier B. 2002. Fungal growth and Fusarium mvcotoxin content in isogonic traditional maize and genetically modified maize grown in France and Spain. Journal of agricultural and food chemistry 50(4): 728-731. 9. Aulrich K, Bohme H, Daenicke R, Halle I, Flachowsky G. 2001. Genetically modified feeds in animal nutrition 1st communication: Bacillus thuringiensis (Bt) corn in poultry, pig and ruminant nutrition. Archie f it Tierernahrung (Archives of Animal Nutrition) 54(3):183-195. 10. Bohme I I, Aulrich K, Daenicke R, Flachowsky G. 2001. Genetically modified feeds in animal nutrition. 2nd communication: glufosinate tolerant sugar beets (roots and silage) and maize grains for ruminants and pigs. Archly fiir Tierernahrung(Archives of animal nutrition) 54(3):197-207. 11. Arencibia A, Gentinetta E, Cuzzoni E, Castiglione S, Kohli A, Vain P, Leech M, Christou P, Sala F. 1998. Molecular analysis of the genome of transgenic rice (Oryza sativa L.)plants produced via particle bombardment or intact cell electroporation. Molecular breeding 4(2):99-109. 12. Bub A, Moseneder J, Wenzel G, Rechkemmer G, Briviba K. 2008. Zeaxanthin is bioavailable from genetically modified zeaxanthin-rich potatoes. European journal of nutrition 47(2):99-103. 13. Catchpole GS, Beckmann M, Enot DP, Mondhe M, Lvwicki B, Taylor J, I lardy N, Smith A, King RD, Kell [)B, Fiehn 0, Draper J. 2005. Hierarchical metabolomics demonstrates substantial compositional similarity between genetically modified and conventional potato crops. PNAS 102(40):14458-62. (full text) The metabolite analysis and statistical work was funded by the Food Standards Agency (London) as part of its G02006 project. 14. Chambers PA, Duggan l S, Heritage J, Forbes JM. 2000. The fate of antibiotic resistance marker genes in transgenic plant feed material fed to chickens. Journal of antimicrobial chemotherapy 49(1):161-164. Novartis, formerly Ciba-Geigy, provided the genetically modified maize seeds used in this study. This work was funded by a grant from the Food Standards Agency. 15. Chen ZL, Gu Il, Li Y, Su Y, Wu P, Jiang Z, Ming X, Tian J, Pan N, Qu LJ. 2003. Safety assessment for genetically modified sweet pepper and tomato. Toxicology 188(2-3):297- 307. 16. Cheng KC, Beaulieu J, Iquira F, Belzile FJ, Fortin MG, Stromvik MV. 2008. Effect of trans<eenes on global gene expression in soybean is within the natural range of variation of conventional cultivars. Journal of agricultural and food chemistry 56(9):3057-67. 17. Chowdhury LH, Kuribara H, [lino A, Sultana P, Mikami 0, Shimada N, Guruge KS, Saito M, Nakajima Y. 2003. Detection of corn intrinsic and DNA fragments and CrylAb protein in the gastrointestinal contents of pigs fed genetically modified corn Btl I. Journal of animal science 81(10):2546-2551. (full text) 18. Chowdhury EH, Mikami 0, Murata H, Sultana P, Shimada N, Yoshioka M, Guruge KS, Yamamoto S, Miyazaki S, Yamanaka N, Nakajima Y. 2004. Fate of maize intrinsic and recombinant genes in calves fed genetically modified maize Bt 1. Journal of food protection 67(2):365-370. 19. Chowdhury EH, Shimada N, Murata H, Mikami 0, Sultana P, Miyazaki S, Yoshioka M, Yamanaka N, Hirai N,Nakajima Y.(2003). Detection of CrylAb protein in gastrointestinal contents but not visceral organs of genetically modified Btl 1-fed calves. Vet Hum Toxicol. 2003 Mar;45(2):72-5. 20. Chrenkova M, Sommer A, Ceresnakova Z, Nitrayova S, Prostredna M (2002)Nutritional evaluation of genetically modified maize corn performed on rats. Archives of Animal Nutrition-Archiv fur Tierernahrung 56:229-235 Institute of Animal Nutrition, Research Institute of Animal Production, Hlohovska 2, 949 92 Nitra, Slovak Republic. chrenko @vuzv.sk 21. Cleveland, Thomas E, Patrick F Dowd, Anne E Desjardins, Deepak Bhatnagar, Peter J Cotty (2003). United States Department of Agriculture—Agricultural Research Service research on pre-harvest prevention of mycotoxins and mycotoxigenic fungi in US crops, Pest Management Science Volume 59, Issue 6-7 , Pages 629—642 22. Daenicke R, Aulrich K, Flachowsky G. (1999). GMO in animal feedstuffs: nutritional properties of Bt-maize... Mais: Fachzeitschrift uber Forschung, Produktionstechnik, Verwertung and Okonomik 135-137 Institute of Animal Nutrition, Federal Agricultural Research Centre Braunschweig (FAL), Germany. 23. Defernez M, Gunning YM, Parr AJ, Shepherd LV, Davies HV, Colquhoun IJ. (2004) J Agric Food Chem. 2004 Oct 6;52(20):6075-85. NMR and HPLC-UV profiling of potatoes with genetic modifications to metabolic pathways. 24. Di Carli M, Villani ME, Renzone G,Nardi L, Pasquo A, Franconi R, Scaloni A, Benvenuto E, Desiderio A. (2008). Leaf Proteome Analysis of Transgenic Plants Expressing Antiviral Antibodies. J Proteome Res. 2008 Dec 19. [Epub ahead of print] Systematic analysis of protein profiles to indentify any unexpected changes. 25. Dowd, Patrick F (2000). Indirect Reduction of Ear Molds and Associated Mycotoxins in Bacillus thuringiensis Corn Under Controlled and Open Field Conditions: Utility and Limitations, Journal of Economic Entomology Volume 93, Issue 6 (December 2000) pp. 1669-1679 Bioactive Agents Research Unit, USDA-ARS, National Center for Agricultural Utilization Research, 1815 N. University Street, Peoria, IL 61604 26. Dowd PF (2001) Biotic and abiotic factors limiting efficacy of Bt corn in indirectly reducing mycotoxin levels in commercial fields. J Econ Ent 94(5): 1067-1074. 27. Dubouzet JG, Ishihara A, Matsuda F, Miyagawa H, Iwata H, Wakasa K.(2007) Integrated metabolomic and transcriptomic analyses of high-tryptophan rice expressing a mutant anthranilate synthase alpha subunit. J Exp Bot. 2007;58(12):3309-21. Epub 2007 Sep 4. 28. Duggan, P.S., Chambers, P.A., Heritage, J., Forbes, J.M. (2002). Survival of free DNA encoding antibiotic resistance from transgenic maize and the transformation activity of DNA in ovine saliva, ovine rumen fluid and silage effluent. FEMS Microbiol. Lett. 191, 71-77. 29. Enot DP Manfred Beckmann, David Overy, and John Draper(2006) Predicting interpretability of metabolome models based on behavior, putative identity, and biological relevance of explanatory signals PNAS October 3, 2006 vol. 103(40): 14865- 14870 30. Ewen SWB, Pusztai A (1999). Effect of diets containing genetically modified potatoes expressing Galanthus nivalis lectin on rat small intestine. Lancet 354:1353-1354 31. Finamore A, Roselli M, Britti S, Monastra G, Ambra R, Turrini A, Mengheri E.(2008) Intestinal and Peripheral Immune Response to MON810 Maize Ingestion in Weaning and Old Mice. J Agric Food Chem. 2008 Nov 14. [Epub ahead of print] PMID: 19007233 32. Flachowsky G, Halle I, Aulrich K Long term feeding of Bt-corn—a ten-generation study with quails. Arch Anim Nutr. 2005 Dec;59(6):449-51. Institute of Animal Nutrition, Federal Agricultural Research Centre, Braunschweig, Germany. gerhard.flachowsky @fal.de also see (REVIEW) Flachowsky G, Chesson A, Aulrich K. Animal nutrition with feeds from genetically modified plants. 33. Gregersen PL, Brinch-Pedersen H, Holm PB.(2005) A microarray-based comparative analysis of gene expression profiles during grain development in transgenic and wild type wheat. Transgenic Res. 2005 Dec;14(6):887-905. 34. Gizzarelli F, Corinti S, Barletta B, lacovacci P, Brunetto B, Butteroni C, Afferni C, Onori R, Miraglia M, Panzini G, Di Felice G, Tinghino R. (2006) Evaluation of allergenicity of genetically modified soybean protein extract in a murine model of oral allergen-specific sensitization. Clin Exp Allergy. 2006 Feb;36(2):238-48. 35. Halle, I., K. Aulrich and G. Flachowsky. 2004. Four generations of feeding of GMO-corn to breeder quail. (Futterung von gentechnisch verandertem Mais an Zuchtwachtein fiber vier Generationen). Proc. Soc. Nutr. Physiol. 13:124. Institute of Animal Nutrition, Federal Agricultural Research Centre (FAL), Braunschweig, Germany. 36. Jenkins Helen, Nigel Hardy, Manfred Beckmann, John Draper, Aileen R. Smith, Janet Taylor, Oliver Fiehn, Royston Goodacre, Raoul J. Bino, Robert Hall, Joachim Kopka, Geoffrey A. Lane, B. Markus Lange, Jang R. Liu, Pedro Mendes, Basil J. Nikolau, Stephen G. Oliver,Norman W. Paton, Sue Rhee, Ute Roessner-Tunali, Kazuki Saito, Jern Smedsgaard, Lloyd W. Sumner, Trevor Wang, Sean Walsh, Eve Syrkin Wurtele, Douglas B. Kell.(2004) A proposed framework for the description of plant metabolomics experiments and their results. Nature Biotechnology 22, 1601-1606. Under UK Food Safety Authority G02006: Metabolome technology for the profiling of GM and conventionally bred plant materials 37. Jia, Shirong, Feng Wang Lei Shi Qianhua Yuan Wuge Liu Yilong Liao Shuguang Li Wujun Jin Huipu Peng. 2007. Transgene flow to hybrid rice and its male-sterile lines Transgenic Res 16:491-501. 38. Kilic A, Akay M T. 2008. A three generation study with genetically modified Bt corn in rats: Biochemical and histopathological investigation Food and Chemical Toxicology 46:1164-1170. 39. Kleter,Gijs A., Ad A. C. M. Peijnenburg, and Henk J. M. Aarts. 2005. Health considerations regarding horizontal transfer of microbial transgenes present in genetically modified crops. Journal of Biomedicine and Biotechnology 4 (2005) 326-352. 40. Kleter GA, Bhula R, Bodnaruk K, Carazo E, Felsot AS, Harris CA, Katayama A, Kuiper HA, Racke KD, Rubin B, Shevah Y, Stephenson GR, Tanaka K, Unsworth J, Wauchope RD, Wong SS. 2007. Altered pesticide use on transgenic crops and the associated general impact from an environmental perspective. Pest Manag Sci 63(11):1107-15. 41. Kleter GA, Peijnenburg AA. 2002. Screening of transgenic proteins expressed in transgenic food crops for the presence of short amino acid sequences identical to potential, IgE-binding linear epitopes of allergens. BMC Struct Biol 2:8. 42. Kuiper HA, Hub P J M Noteborn, and ACM Peijnenburg. 1999 Adequacy of methods for testing the safety of genetically modified foods. Lancet 354:1315-6. 43. Le Gall, Gwenaelle, M. Susan DuPont, Fred A. Mellon, Adrienne L. Davis, Geoff J. Collins, Martine E. Verhoeyen, and Ian J. Colquhoun. 2003. Characterization and Content of Flavonoid Glycosides in Genetically Modified Tomato (Lycopersicon esculentum) Fruits J. Agric. Food Chem 51(9):2438 -2446. 44. Le Gall G, Colquhoun IJ, Davis AL, Collins GJ, Verhoeyen ME. 2003. Metabolite profiling of tomato (Lycopersicon esculentum) using 1H NMR spectroscopy as a tool to detect potential unintended effects following a genetic modification. J Agric Food Chem 51(9):2447-56. Erratum in: 2004. J Agric Food Chem 52(10):3210. 45. Lehesranta,Satu J., Howard V. Davies, Louise V.T. Shepherd,Naoise Nunan, Jim W. McNicol, Seppo Auriola, Kaisa M. Koistinen, Soile Suomalainen, Harri 1. Kokko and Sirpa O. Karenlampi. 2005. Comparison of Tuber Proteomes of Potato Varieties, Landraces, and Geneticallyn Modified Lines. Plant Physiology 138:1690-1699. 46. Li X, Huang K, He X, Zhu B, Liang Z, Li H, Luo Y. 2007. Comparison of nutritional quality between Chinese indica rice with sck and crylAc genes and its nontransgenic counterpart.J Food Sci. 2007 Aug;72(6):S420-4. 47. Malatesta M, Boraldi F, Annovi G, Baldelli B, Battistelli S, Biggiogera M, Quaglino D. 2008. A long-term study on female mice fed on a genetically modified soybean: effects on liver ageing.Histochem Cell Biol. 48. Brown NM and Setchell KDR. 2001. Animal models impacted by phytoestrogens in commercial chow: implications for pathways influenced by hormones. Laboratory Investigation 81:735-747. "All investigators should be vigilant to the phytoestrogen composition of commercial rodent diets because there is a history of potent biological effects in larger animals and humans from high circulating isoflavone concentrations" 49. Thigpen JE. 2004. Selecting the appropriate rodent diet for endocrine disruptor research and testing studies. ILAR Journal. 45:401-416. 50. Malatesta M, Tiberi C, Baldelli B, Battistelli S, Manuali E, Biggiogera M. 2005. Reversibility of hepatocyte nuclear modifications in mice fed on genetically modified soybean. Eur J Histochem 49(3):237-42. 51. Momma K, Hashimoto W, Yoon HJ, Ozawa S, Fukuda Y, Kawai S, Takaiwa F, Utsumi S, Murata K. 2000. Safety assessment of rice genetically modified with soybean glycinin by feeding studies on rats. Biosci Biotechnol Biochem. 64:1881-6. 52. Montero M, Coll A, Nadal A, Messeguer J, Pla M. Only half the transcriptomic differences between resistant genetically modified and conventional rice are associated with the transgene. Plant Biotechnology, 29 OCT 2010 DOI: 10.1111/j.1467- 7652.2010.00572.x. 53. Peterson, Robert K.D. and Leslie M. Shama 2005. A Comparative Risk Assessment of Genetically Engineered, Mutagenic, and Conventional Wheat Production Systems Transgenic Research 14 (6) p859-875. This study was funded solely by a USDA Special Research Grant to the Institute for Biobased Products and by the Montana Agricultural Experiment Station, Montana State University. 54. Phipps RH, Deaville ER, Maddison BC (2003) Detection of transgenic and endogenous plant DNA in rumen fluid, duodenal digesta, milk, blood, and feces of lactating dairy cows. Journal of Dairy Science 86:4070-4078. Funded by the U.K. Food Standards Agency. 55. Ramessar, Koreen, Ariadna Peremarti Sonia Go'mez-Galera Shaista Naqvi Marian Moralejo Pilar Munoz Teresa Capell Paul Christou 2007. Biosafety and risk assessment framework for selectable marker genes in transgenic crop plants: a case of the science not supporting the politics, Transgenic Res 16:261-280. This work was funded in part through the EU FP6 Pharma-Planta project. 56. Rhee, G.S., Cho, D.H., Won, Y.H., Seok, J.H., Kim, S.S., Kwack, S.J., Lee, R.D., Chae, S.Y., Kim, J.W., Lee, B.M., Park, K.L., Choi, K.S., 2005. Multigeneration reproductive and developmental toxicity study of bar gene inserted into genetically modified potato on rats. J. Toxicol. Environ. Health A 68, 2263-2276. 57. Knudsen I, Poulsen M. 2007. Comparative safety testing of genetically modified foods in a 90-day rat feeding study design allowing the distinction between primary and secondary effects of the new genetic event. Regul Toxicol Pharmacol 49(1):53-62. 58. Lutz B, Wiedemann S, Einspanier R, Mayer J, Albrecht C. 2005. Degradation of CrylAb protein from genetically modified maize in the bovine gastrointestinal tract. Journal of Agricultural and Food Chemistry 53:1453-1456. This addresses the digestibility of an insect detection protein which is believed to be an indicator of allergenicity risk. Risks of allergenicity are one of the major concerns raised by people who are worried about the safety of genetically engineered food 59. Rang A, Linke B and Jansen B. 2005. Detection of RNA variants transcribed from the transgene in Roundup Ready soybean, European Food Research and Technology 220(3- 4):438-443. 60. Reuter T, Aulrich K, Berk A, Flachowsky G. 2002. Investigations on genetically modified maize (Bt-maize) in pig nutrition: chemical composition and nutritional evaluation. Arch Tierernahr 56(1):23-31. 61. Rosati, A, Bogani P (2008) Characterisation of 3'transgene insertion site and derived mRNAs in MON810 YieldGard® maize Plant Molecular Biology 67:271-281. Dr. G. Monastra provided seeds of MON810 and isogenic control maize. This work was supported by a grant from MIPAF (Ministero delle Politiche Agricole, Alimentari e Forestali), Project: `OGM in Agricoltura. 62. Sakamoto, Y; Tada, Y; Fukumori,N; Tayama, K; Ando, H; Takahashi, H; Kubo, Y; Nagasawa, A; Yano, N; Yuzawa, K; Ogata, A; Kamimura, H. 2007. A 52-week feeding study of genetically modified soybeans in F344 rats Journal of the Food Hygiene Society of Japan, 48 (3): 41-50. 63. Sakamoto Y, Tada Y, Fukumori N, Tayama K, Ando H, Takahashi H, Kubo Y, Nagasawa A, Yano N, Yuzawa K, Ogata A.A 2008. 104-week feeding study of genetically modified soybeans in F344 rats. Shokuhin Eiseigaku Zasshi. 49(4):272-82. 64. Shepherd LV, McNicol JW, Razzo R, Taylor MA, Davies HV (2006). Assessing the potential for unintended effects in genetically modified potatoes perturbed in metabolic and developmental processes. Targeted analysis of key nutrients and anti-nutrients. Transgenic Res. 15(4):409-25. 65. Shimada N, Murata H, Mikami 0, Yoshioka M, Guruge KS, Yamanaka N,Nakajima Y, Miyazaki S. 2006. Effects of feeding calves genetically modified corn btl 1: a clinico- biochemical study.J Vet Med Sci. 2006 Oct;68(10):1 1 13-5. 66. Sinagawa-Garcia SR, Rascon-Cruz Q, Valdez-Ortiz A, Medina-Godoy S, Escobar- Gutierrez A, Paredes-Lopez 0. 2004. Safety assessment by in vitro digestibility and allergenicity of genetically modified maize with an amaranth 11S globulin. J Agric Food Chem. 2004 May 5;52(9):2709-14. 67. Schroder M, Poulsen M, Wilcks A, Kroghsbo S, Miller A, Frenzel T, Danier J, Rychlik M, Emami K, Gatehouse A, Shu Q, Engel KH, Altosaar I, Knudsen I. A 90-day safety study of genetically modified rice expressing CrylAb protein (Bacillus thuringiensistoxin) in Wistar rats. Food Chem Toxicol. 2007 Mar;45(3):339-49. 68. Scientific Opinion of the Panel on Genetically Modified Organisms [EFSAJ(Question No EFSA-Q-2008-077) Adopted on 29 October 2008, SCIENTIFIC OPINION Request from the European Commission related to the safeguard clause invoked by France on maize MON810 according to Article 23 of Directive 2001/18/EC and the emergency measure according to Article 34 of Regulation No 1829/2003/EC 1. The EFSA Journal (2008) 850, 1-45 69. Sten E, Skov PS, Andersen SB, Torp AM, Olesen A, Bindslev-Jensen U, Poulsen LK, Bindslev-Jensen C. 2004. A comparative study of the allergenic potency of wild-type and glyphosate-tolerant gene-modified soybean cultivars. APMIS. 2004 Jan;112(1):21-8. This study is part of the projects "BioRisk", supported by the Danish Medical Research council, and "EpiPat", supported by the Danish Ministry of Food. 70. Takahashi, H. Hotta, Y. Hayashi, M. Kawai-Yamada, M. Komatsu, S. Uchimiya, H. 2005. High throughput metabolome and proteome analysis of transgenic rice plants (Oryza sativa L.). Plant Biotechnol 22, 47-50. 71. Taylor, J., King, R. D., Altmann, T. & Fiehn, 0.(2002) Application of metabolomics to plant genotype discrimination using statistics and machine learning. Bioinformatics 18, S241-S248 (2002).1IK Food Safety Authority Under G02006: Metabolome technology for the profiling of GM and conventionally bred plant materials 72. Tony MA, Butschke A, Broll H, Grohmann L, Zagon J, Halle I, Danicke S, Schauzu M, Hafez HM, Flachowsky G. Safety assessment of Bt 176 maize in broiler nutrition: degradation of maize-DNA and its metabolic fate. Arch Tierernahr. 2003 Aug;57(4):235- 52. 73. Venneria E, Simone Fanasca, Giovanni Monastra, Enrico Finotti, Roberto Ambra, Elena Azzini, Alessandra Durazzo, Maria Stella Foddai, and Giuseppe Maiani (2008) Assessment of the Nutritional Values of Genetically Modified Wheat, Corn, and Tomato Crops J. Agric. Food Chem. 74. Wakasa K, Hasegawa H, Nemoto H, Matsuda F, Miyazawa H, Tozawa Y, Morino K, Komatsu A, Yamada T, Terakawa T, Miyagawa H.2006. High-level tryptophan accumulation in seeds of transgenic rice and its limited effects on agronomic traits and seed metabolite profile.J Exp Bot. 2006;57(12):3069-78. 75. Weekes, Rebecca, Theodore Allnutt, Caroline Boffey, Sarah Morgan, Mark Bilton, Roger Daniels and Christine Henry (2008) A study of crop-to-crop gene flow using farm scale sites of fodder maize ( Zea mays L.) in the UK Transgenic Res (2007) 16: 203- 211. Funded by Defra (project EPG 1/5/138). Bayer CropScience provided the positive control T25 maize seed. 76. Windels P, Taverniers I, Depicker A, Van Bockstaele E, De Loose M (2001) Characterisation of the Roundup Ready soybean insert Eur Food Res Technol 213:107- 112. 77. Zhang, Jun, Lin Cai, Jiaqin Cheng, Huizhu Mao, Xiaoping Fan, Zhaohong Meng, Ka Man Chan, Huijun Zhang, Jianfei Qi, Lianghui Ji and Yan Hong (2008) Transgene integration and organization in Cotton ( Gossypium hirsutum L.) genome Transgenic Research 17 (2) 293-306. This project was supported by an internal research grant of Temasek Life Sciences Laboratory, Singapore. Although cotton is a fibre crop it is also a vegetable oil crop. 78. Zhu Y, Li D, Wang F, Yin J, Jin H (2004)Nutritional assessment and fate of DNA of soybean meal from Roundup Ready or conventional soybeans using rats. 79. Zolla L, Rinalducci S, Antonioli P, Righetti PG.(2008) Proteomics as a complementary tool for identifying unintended side effects occurring in transgenic maize seeds as a result of genetic modifications. J Proteome Res. 2008 May;7(5):1850-61. 80. Zywicki Britta , Gareth Catchpole, John Draper, and Oliver Fiehn. 2004. Comparison of rapid LC-ESI-MS/MS methods for determination of glycoalkaloids in transgenic field grown potatoes. Analytical Biochemistry . UK Food Safety Authority Under G02006: Metabolome technology for the profiling of CM and conventionally bred plant materials 81. Ute Vogler, Anja S. Rott, Cesare Gessler& Silvia Dorn. How transgenic and classically bred apple genotypes affect non-target organisms on higher trophic levels. Entomologia Experimentalis et Applicata Volume 134 Issue 2, Pages 114— 121 82. Coll A,Nadal A, Collado R, Capellades G, Kubista M, Messeguer J, Pla M. Natural variation explains most transcriptomic changes among maize plants of MON810 and comparable non-GM varieties subjected to two N-fertilization farming practices. Plant Mol Biol. 2010 Jun;73(3):349-62. Epub 2010 Mar 27. 83. Wiedemann S, CGiirtler P, Albrecht C. 2007. Effect of feeding cows genetically modified maize on the bacterial community in the bovine rumen. Applied and environmental microbiology 73(24):8012-7. 84. Transgene x Environment Interactions in Genetically Modified Wheat 85. Are GM and conventionally bred cereals really different? 86. Borejsza-Wysocka et al., Stable expression and phenotypic impact of attacin F. transgene in orchard grown apple trees over a 12 year period BMC Biotechnology 2010, 10:41 87. Coll A, Nadal A, Collado R, Capellades G, Messeguer J, Mele E. Palaudelmas M, Pla M (2009) Gene expression profiles of MON810 and comparable non-GM maize varieties cultured in the field are more similar than are those of conventional lines. Transgcnic Res 18:801-808 88. Andreas Lindfeld, Corsin Lang, Eva Knop, Wolfgang Nentwig, Hard to digest or a piece of cake? Does GM wheat affect survival and reproduction of Enchvtraeus albidus, (Annelida: Enchytraeidae)?, Applied Soil Ecology, Volume 47, Issue 1, January 2011, Pages 51-58, ISSN 0929-1393, DOI: 10.1016/j.apsoil.2010.10.012. 89. S. von Burg, F. J. F. van Veen, F. Alvarez-Alfageme, J. Romeis. Aphid-parasitoid community structure on genetically modified wheat. Biology Letters, 2011; DOI: 10.1098/rsb1.2010.1 147 90. Kusano M, Redestig H, Hirai T, Oikawa A, Matsuda F, Fukushima A, Arita M, Watanabe S, Yano M, Hiwasa-Tanase K, Ezura H, Saito K. Covering chemical diversity of genetically-modified tomatoes using metabolomics for objective substantial equivalence assessment. PLoS One. 2011 Feb 16:6(2):e16989. 91. Jose L. Domingo, Jordi Gine Bordonaba, A literature review on the safety assessment of genetically modified plants, Environment International, Volume 37, Issue 4, May 2011, Pages 734-742, ISSN 0160-4120, DOI: 10.1016/j.envint.20I 1.01.003. Review covers feeding studies from 2007-2010 (but no 2010 papers included). 92. Yuan Y, Xu W, Luo Y, Liu H, Lu J, Su C, Huang K. Effects of genetically modified T2A-1 rice on faecal microflora of rats during 90 day supplementation. J Sci Food Agric. 2011 Apr 26. doi: 10.1002/jsfa.4421. [Epub ahead of print] 93. Stuart J. Smyth, Michael Gusta, Kenneth Belcher, Peter W.B. Phillips and David Castle. Environmental impacts from herbicide tolerant canola production in Western Canada. Agricultural Systems, Volume 104, Issue 5, June 2011, Pages 403-410 94. Duan JJ, Marvier M, Huesing J, Dively G, Huang ZY, 2008 A Meta-Analysis of Effects of Bt Crops on Honey Bees (Hymenoptera: Apidae). PLoS ONE 3(1): e1415. doi:10.1371/journal.pone.0001415 95. Sishuo Cao, Wentao Xu, YunBo Luo, Xiaoyun He, Yanfang Yuan, Wenjun Ran, Lixing Lianga and Kunlun Huang. Metahonomics study of transgenic Bacillus thuringiensis rice (T2A-l) meal in a 90-day dietary toxicity studv in eats,Mol. BioSyst., 2011, DOI: 10.1039/C 1 MB05076A (May 19, 2011) 96. Helga Gruber, Vijay Paul, Patrick Guertler, Hubert Spiekers, Ales Tichopad, Heinrich H. D. Meyer, and Martin Muller. Fate ofCrylAb Protein in Agricultural Systems under Slurry Management of Cows Fed Genetically Modified Maize (Zea mays L.) MON810: A Quantitative Assessment.J. Agric. Food Chem., Article ASAP DOI: 10.1021/jf200854n Publication Date (Web): May 23, 2011 97. Lin, B., Tan, Z., Xiao, G., Wang, M., Cong, Z., Wang, S., Tang, S., Zhou, C., Sun, Z. and Wang, W. (2009), Evaluation of compositional and nutritional equivalence of genetically modified rice to conventional rice using in situ and in vitro techniques. Journal of the Science of Food and Agriculture, 89: 1490-1497. doi: 10.1002/jsfa.3613 98. A. M. Shelton, J.-Z. Zhao, and R. T. Roush Economic, Ecological, Food Safety, and Social Consequences of the deployment of Bt Transgenic Plants. Annual Review of Entomology, Vol. 47: 845-881 (Volume publication date January 2002) 99. D. M. Olson, J. R. Ruberson, A. R. Zeilinger &D. A. Andow, Colonization preference of Luschistus serous and Nezara riridula in transgenic cotton varieties. peanut, and soybean. Entomologia Experimentalis et Applicata 139: 161-169, 2011 100. Fangneng Huang, David A. Andow& Lawrent L. Buschman. Success of the high- dose/refuge resistance management strategy after 15 years of Bt crop use in North America. Entomologia Experimentalis et Applicata 140: 1-16, 2011 101. Alvarez-Alfageme F, von Burg S, Romeis J, 2011 Infestation of Transgenic Powdery Mildew-Resistant Wheat by Naturally Occurring Insect Ilerbivores under Different Environmental Conditions. PLoS ONE 6(7): e22690. doi:10.1371/journal.pone.0022690 102. Tang M, Xie T, Cheng W, Qian L, Yang S, Yang D, Cui W, Li K. A 90-day safety study of genetically modified rice expressing rhIGF-I protein in C57BL/6.1 rats. Transgenic Res. 2011 Sep 11. 103. Gruber FI., Paul V., Meyer H.H.D., Muller M. (201 1) Determination of insecticidal Cryl Ab protein in soil collected in the final growing seasons of a nine-year field trial of Bt-maize MON810. Transgenic Res. 2011 Apr 16 104. Duc C,Nentwig W, Lindfeld A, 2011 No Adverse Effect of Genetically Modified Antifungal Wheat on Decomposition Dynamics and the Soil Fauna Community—A Field Study. PLoS ONE 6(10): e25014. doi:10.1371/journal.pone.0025014 105. Rose R, Dively GP. Effects of insecticide-treated and Lepidopteran-active Bt transgenic sweet corn on the abundance and diversity of arthropods. Environ Entomol. 2007 Oct;36(5):1254-68. 106. Powell M, Wheatley AO, Omoruyi F, Asemota RN, Williams NP, Tennant PF. Comparative effects of dietary administered transgenic and conventional papaya on selected intestinal parameters in rat models. Transgenic Res. 2010 Jun;19(3):51 1-8. Epub 2009 Aug 19. 107. Matilde Eizaguirre, Ramon Albajes, Carmen Lo' pez, Jordi Eras, Bele'n Lumbierres & Xavier Pons. Six years after the commercial introduction of Bt maize in Spain: Held evaluation, impact and future prospects Transgenic Research (2006) 15:1-12 DOI 10.1007/s11248-005-3998-1 108. M. K. Dhillion and H. C. Sharma. Impact of'Bt-engineered cotton on target and non-target_arthropods, toxin flow through different trophic levels and seedcotton yield. Karnataka J. Agric. Sci., 22(3-Spl. Issue ) : (462-466 ) 2009 109. Marvier M, McCreedy C, Regetz J, Kareiva P. A meta-analysis of effects of Bt cotton and maize on nontarget invertebrates. Science 316, 1475 (2007); DOI: 10.1126/science.1139208 110. Manda G. Cattaneo, Christine Yafuso, Chris Schmidt, Cho-ying Huang, Magfurar Rahman, Carl Olson, Christa Ellers-Kirk, Barron J. Orr, Stuart E. Marsh, Larry Antilla, Pierre Dutilleul, and Yves Carriere Y. Farm-scale evaluation of the impacts of transgenic cotton on hiodiversity, pesticide use, and yield. Proc Natl Acad Sci U S A. 2006 May 16;1 03(20):7571-6. Epub 2006 May 4. 111. B. Anilkumar, A. Gopala Reddy, B. Kalakumar, M. Usha Rani, Y. Anjaneyulu, T. Raghunandan, Y. Ramana Reddy, K. Jyothi, and K. S. Gopi. Sero-biochemical studies in sheep fed with Bt cotton plants. Toxicol Int. 2010 Jul—Dec; 17(2): 99-101. doi: 10.4103/0971-6580.72680. (local PDF) 112. Mohanta RK, Singhal KK, Tyagi AK, Rajput YS, Prasad S. Nutritional evaluation oftransgenic cottonseed in the ration of lactating dairy cows. Trop Anim Health Prod. 2010 Mar;42(3):431-8. Epub 2009 Aug 24. 113. Sarkar B, Patra AK, Purakayastha TJ, Megharaj M. Assessment of biological and biochemical indicators in soil under transgenic Bt and non-Bt cotton crop in a sub- tropical environment. Environ Monit Assess. 2009 Sep;156(1-4):595-604. Epub 2008 Aug 22. 114. Qaim, M. Benefits of genetically modified crops for the poor: household income, nutrition, and health. (PDF)New Biotechnology Volume 27, Issue 5, 30 November 2010, Pages 552-557 115. Chelsea, S., et al. Assessment of the health impact of GM plant diets in long-term and multiuenerational animal feeding trials: A literature review. Food Chem. Toxicol. (2011), doi:10.1016/j.fct.2011.11.048 116. Maria C. Walsh, Stefan G. Buzoianul, Gillian E. Gardiner, Mary C. Rea, R. Paul Ross, Joseph P. Cassidy and Peadar G. Lawlor. Effects of short-term feeding of Bt MON810 maize on growth performance. organ morphology and function in pigs. British Journal of Nutrition (2012), 107, 364-371 doi:10.1017/5000711451100301 1 117. McCallum EJ, Cunningham JP, Lucker J, Zalucki MP, De Voss JJ, Botella JR. Increased plant volatile production affects oviposition, but not larval development, in the moth Flelicoverpa armiuera. J Exp Biol. 2011 Nov 1;214(Pt 21):3672-7 PMID 21993797 118. Walsh MC, Buzoianu SG, Gardiner GE, Rea MC, Gelencser E, et al. (2011) Fate of Transgenic DNA from Orally Administered Bt MON810 Maize and Effects on Immune Response and Growth in Pius. PLoS ONE 6(11): e27177. doi:10.1371/journal.pone.0027177 119. Gao MQ, Hou SP, Pu DQ, Shi M, Ye GY, Chen XX. Multi-generation effects of Bt rice on Anagrusnilapau_vatae, a parasitoid of the nontarget pest Nilapavartaluuens. Environ Entomol. 2010 Dec;39(6):2039-44. PMID 22182572 120. Michaela Prischl, Evelyn Hackl, Milica Pastar, Stefan Pfeiffer, Angela Sessitsch, Genetically modified Bt maize lines containinu cry 3Bb 1. cry 1 A 105 or cry l Ab2 do not affect the structure and functioning of root-associated endophvte communities, Applied Soil Ecology, Volume 54, March 2012, Pages 39-48, ISSN 0929-1393, 10.1016/j.apsoil.2011.12.005. 121. Olivier Sanvido, Jorg Romeis, Achim Gathmann, Marco Gielkens, Alan Raybould, Franz Bigler, Evaluating environmental risks of genetically modified crops: ecological harm criteria for regulatory decision-making, Environmental Science &amp; Policy, Volume 15, Issue 1, January 2012, Pages 82-91, ISSN 1462-9011, 10.1016/j.envsci.201 1.08.006. 122. Calla Fonseca, Sebastien Planchon, Jenny Renaut, Maria Margarida Oliveira, Rita Batista, Characterization of maize allergens --MON8 I 0 vs. its non-transgenic counterpart, Journal of Proteomics, Available online 13 January 2012, ISSN 1874-3919, 10.1016/].j prot.2012.01.005. 123. Ping-Li Dai, Wei Zhou, Jie Zhang, Hong-Juan Cui, Qiang Wang, Wei-Yu Jiang, Ji-Hu Sun, Yan-Yan Wu, Ting Zhou, Field assessment of Bt cry Ah corn pollen on the survival. development and behavior of Apis mellifera ligustica, Ecotoxicology and Environmental Safety, Available online 23 February 2012, ISSN 0147-6513, 10.1016/j.ecoenv.2012.01.005. 124. Jaimie Schnell, He'le'ne Labbe',Nik Kovinich, Yuzuki Manabe, Brian Miki. Comparability of imazapyr-resistant Arabidopsis created by transgenesis and mutagenesis. Transgenic Res. 2012 DOI 10.1007/s11248-012-9597-z 125. Tian J-C, Chen Y, Li Z-L, Li K, Chen M, et al. (2012) Transgenic Cry I Ab Rice Does Not Impact Ecological Fitness and Predation of a Generalist Spider. PLoS ONE 7(4): e35164. doi:10.1371/journal.pone.0035164 126. Cheeke TE, Rosenstiel TN, Cruzan MB. Evidence of Reduced Arbuscular Mycorrhizal Fungal Colonization in Multiple Lines of Bt Maize. Am. J. Bot. April 2012 vol. 99 no. 4 700-707. doi: 10.3732/ajb.1100529 Fact Sheet about Food Safety Issues of Genetically Engineered (GE) Crops Dr. Susan C. Miyasaka, Agronomist Dr. Russell Nagata, Plant Breeder "Foods consumed today are derived from plants and animals whose genetic makeup has been modified by sexual crosses and mutation. Recombinant DNA provides a new tool to make genetic modifications, and this technology is termed genetic engineering or biotechnology. (Lemaux, 2008)" "The safety of genetically engineered crops and foods,just as those created by classical breeding and mutation and grown conventionally or organically, needs to be evaluated on a case-by-case basis so that informed decisions can be made about their utility, safety, and appropriateness. (Lemaux, 2008)" What are the risks of eating transgenes? No negative effects on food safety have been found in commercialized GE crops. "To date, no scientifically valid demonstrations have shown that food safety issues of foods containing genetically engineered (GE) ingredients are greater than those from conventionally or organically produced foods. (Lemaux, 2008)" "Extensive risk assessment and safety testing of crops developed through the use of genetic engineering has shown that there are no varieties in use that pose risks to consumers. (Wieczorek and Wright, 2012)" "No reproducible data has shown that transgene DNA from commercialized GE crops behave differently than native plant DNA. (Lemaux, 2008)." "It was concluded that the transgenic soybean diet had no negative effect on fetal, postnatal, pubertal or adult testicular development [of mice]. (Brake and Evenson, 2004)" Do GE foods have changes in nutritional content? No substantial differences in nutritional content have been found between commercialized GE foods and non-GE foods. Our data show that the contents of nutrients... of GE Rainbow papaya are within the range of those of non-GE papaya and that the Rainbow cultivar is substantially similar to the non-GE cultivar. (Tripathi and others, 2010)" "The results [for Round-up Ready soybeans] demonstrated that the composition of these GE lines is equivalent to that of conventional soybean cultivars in the form consumed by humans. (Lemaux, 2008)" Have allergens been introduced through GE? No allergens have been introduced through commercialized GE crops, due to extensive food safety tests conducted prior to approval by FDA. 1 "Although not mandatory, to date all companies marketing new GE foods have consulted with the FDA and performed recommended analyses to determine if introduced proteins have properties that indicate possible allergenicity, i.e., similarities to known allergens, small size, slow digestibility, and/or high heat stability. (Lemaux, 2008)" "Following accepted allergenicity assessment criteria, our results show that the transgene- derived PRSV CP [Papaya Ring Spot Virus coat protein] does not pose a risk of food allergy. (Fermin and others, 2011)." "in recent years a variety of safety studies were conducted specifically on native Bt proteins to show that they do not have characteristics of food allergens or toxins. (Lemaux, 2008)" Can GE foods fed to animals result in transfer of transgenes to animals? DNA and proteins are broken down in the digestive tract. There is no scientific evidence to date that shows that transgenes or their products are transferred to animals fed GE foods or excreted from animals fed GE foods. "To date a large number of experimental studies with livestock have shown that rDNA [recombinant DNA] fragments or proteins derived from GM plants have not been detected in tissues, fluids or edible products of farm animals (Lemaux, 2008)." Can GE foods increase antibiotic resistance in human and animal intestinal flora? There is no scientific evidence to date that GE foods can transfer antibiotic resistance to gut bacteria. And current research now allows the removal of selection genes (antibiotic resistance genes) or marker genes (gus gene) from GE plants. "To demonstrate the fate of transgene DNA in humans, the antibiotic resistance gene from GE maize was shown not to transfer to gut bacteria in chickens fed GE maize. (Lemaux, 2008)" Why doesn't the FDA require labeling of GE foods? The FDA does require labeling of GE foods IF the product contains allergens and its source must be named. "If a food contains a new, potentially allergy-causing introduced protein, the label must state that the product contains the allergen and name its source. (Lemaux, 2008)." Are there positive benefits of GE crops on food safety? Bt corn can be SAFER to eat than non-GE corn, because of less damage due to corn earworms and lower infections of kernels by fungi that contain mycotoxins. "A positive aspect of safety regarding Bt corn is the lower levels of mycotoxins compared with non-Bt corn. Mycotoxins are toxic and carcinogenic chemicals produced as secondary metabolites of fungal colonization that occur as a result of insects such as the corn earworm carrying the mycotoxin containing fungi that infest the kernels following wounding." (Lemaux, 2008) 2 References: Brake, D.G. and D.P. Evenson. 2004. A generational study of glyphosate-tolerant soybeans on mouse fetal, postnatal, pubertal and adult testicular development. Food and Chemical Toxicology. 42:29-356. Fermin, G., R.C. Keith, J.Y. Suzuki, S.A. Ferreira, D.A. Gaskill, K.Y. Pitz, R.M. Manshardt, D. Gonsalves, and S. Tripathi. 2011. Allergenicity assessment of the Papaya Ringspot Virus coat protein expressed in transgenic Rainbow papaya. J. Agr. Food Chem. 59:10006-10012. l.,emaux, P. 2008. Genetically engineered plants and foods: A scientist's analysis of the issues (Part I). Annu. Rev, Plant Biol. 59:771-812. Tripathi, S., J.Y. Suzuki, J.B. Carr, G.T. McQuate, S.A. Ferreira, R.M. Manshardt, K.Y. Pitz, M.M. Wall, and D. Gonsalves. 2011. Nutritional composition of Rainbow papaya, the first commercialized transgenic fruit crop. J. Food Composition and Analysis. 24: 140-147. Wieczorek, A . and M. Wright. 2012. History of Agricultural Biotechnology: How Crop Development has Evolved. Nature Education Knowledge 3(10):9. http://www.naturc.com/scitable/knowledge/I ibrary/history-of-a«ricultural-biotechnoloey-how- crop-development-25885295 3 Fact Sheet on Genetically Engineered Crops–Environmental Issues Susan C. Miyasaka, Agronomist Russell Nagata, Plant Breeder "Genetically engineered (GE) crops and foods have been commercially available in the United States since 1995 and their adoption around the world followed, showing increases each year since their introduction. Whereas the majority of the acreage is in the United States, most farmers who grow these crops reside outside the United States—more than 10 million of the 12 million adopters are in developing countries. These GE crops created by recombinant DNA (rDNA) have been overwhelmingly accepted by farmers, but some consumers remain skeptical. (Lemaux, 2009)" "[T]o date most GE crops on the market harbor Bt [Bacillus thuringensis] and/or HT [Herbicide Tolerance] traits. (Lemaux, 2009)" Can Federal Regulatory Agencies Stop Planting of Genetically Engineered Crops That Pose Environmental Risks? Yes, the FDA, EPA, and USDA are the three federal agencies with responsibilities to ensure that GE crops are safe for consumers and the environment. "GE crops and products made from them are under regulatory control of three federal agencies: the Food and Drug Administration (FDA), the EPA, and the USDA. The FDA is responsible for food safety and labeling of foods and animal feeds from conventional and GE crops. The EPA evaluates food safety and environmental issues associated with new pesticides and pesticidal products, such as Bt corn and the pesticidal Bt product it contains. The EPA's charge also includes GE plants in which a small part of a pest, such as a viral regulatory sequence (e.g., 35S promoter), is used. A division of the USDA, APHIS, oversees environmental safety of planting and field-testing GE plants to ensure GE crop field tests are performed under specified conditions and any unusual occurrences are reported. All three agencies do not oversee each GE crop; however, all have legal rights to demand immediate market removal of any product if valid scientific data show safety concerns for consumers or the environment. (Lemaux, 2009)" Will the Widespread Use of Bt Crops Lead to the Development of Insect Resistance to Bt? Yes, insects have developed resistance to Bt toxins in GE crops, similar to the way that they have developed resistance to Bt insecticides used by conventional and organic farmers. "Bt toxins are also called Cry toxins because they exist as crystals inside the bacterium. Full length Cry toxins are inactive until cleaved to generate their active form in the insect midgut (236, 261)... The precision of Bt proteins for certain insects and their lack of effects in mammals are due to the specificity of receptor binding (Lemaux, 2009)." "The primary strategy in the field for delaying insect resistance to Bt crops is planting refuges of non-Bt crops near Bt crops. Although the strategies implemented to delay resistance have helped sustain efficacy of Bt crops longer than many scientists expected, field-evolved resistance to Bt crops was reported recently. (Lemaux, 2009)" 1 Could GE crops harm non-target organisms, such as butterflies? Yes, in a laboratory study, monarch butterfly caterpillars died when fed milkweed leaves dusted with GE corn pollen containing high levels of Bt. No, in field studies, the EPA concluded that monarch butterflies in and around Bt resistant corn fields were more threatened by widespread use of Bt and other pesticides used in conventional and organic corn crops. In a laboratory study, monarch butterflies died after eating milkweed leaves dusted with pollen from a Bt corn (variety 176). That variety of Bt corn had high levels of Bt in pollen and it has been withdrawn from the market. Other commercial varieties of Bt corn have low levels of Bt in pollen. (Lemaux, 2009) "After reviewing the data, the U.S. EPA concluded there was a very low probability of risk to monarch butterflies beyond 12 feet from the Bt corn field. (Lemaux, 2009)" "The EPA concluded from these studies that Bt corn was not a significant factor in field death of monarch larvae,particularly relative to factors such as the widespread use of pesticides and destruction of the butterfly's winter habitats (Lemaux, 2009)." Could the Use of Herbicide-Tolerant (HT) Genetically Engineered (GE) Crops Lead to `Superweeds'? Yes, herbicide-tolerant (HT)weeds could increase in HT GE cropping systems, similar to other cropping systems that use herbicides. Yes, herbicide tolerant weeds could also develop due to inter-breeding with HT GE crops, such as GE canola and weedy wild relatives. "Crop tolerance to herbicides is achieved (a) by mutations that render a plant not susceptible to the herbicide or (b) through the introduction of transgenes. (Lemaux, 2009). "[P]roblems with herbicide-resistant weeds are real, but not new. These problems have occurred with traditionally bred crops, as well as with HT GE plants. (Lemaux, 2009)" "But herbicide resistance is a problem for farmers regardless of whether they plant GM crops. (Gilbert, 2003)" "HT weeds can also arise because of outcrossing with HT GE crops... Canola, in particular, can naturally form crop-wild hybrids. (Lemaux, 2009)" Does the Use of Genetically Engineered Crops Result in Decreased Use of Pesticides? Yes, GE crops have resulted in significant reductions in the global Environmental Impact (EI) of pesticide applications. Most Herbicide Tolerant (HT) GE crops are tolerant to the herbicide glyphosate. "[G]lyphosate use per acre has increased dramatically from 1995 to 2005, coupled with a concomitant dramatic drop in the use of other herbicides [that were less environmentally friendly]. (Lemaux, 2009)" "Cultivation of GE HT crops has also had other positive effects on the environment, i.e., increases in low- or no-till practices and use in combination with integrated pest management 2 schemes, which were made possible because early season pesticide sprays could be eliminated, allowing beneficial insects to establish. (Lemaux, 2009)" "In summary, numerous studies have been conducted on pesticide usage that analyzed different data sets and methods, sometimes leading to conflicting conclusions. Some studies showed pesticide use, expressed as AI [Active Ingredient] per unit area, decreased with introduction of GE HT and Bt crops; some studies showed increases. More recently, studies have focused on EI and these have shown reductions in El, including on farm workers, consumers, and ecology. (Lemaux, 2009)" "On balance, herbicide-resistant GM crops are less damaging to the environment than conventional crops grown at industrial scale...GM crop technology delivered an 8.9% improvement to the environmental impact quotient—a measure that considers factors such as pesticide toxicity to wildlife (Gilbert, 2003)" Could Genes From Genetically Engineered Plants Move to Bacteria in the Field? Perhaps, over millennia. "Transfer of genes among nonsexually related organisms, e.g., from plants to bacteria, is called horizontal gene transfer...Recent sequence analyses of genes and proteins show that some genes have transferred from plants to bacteria; however, this exchange occurred over a very long evolutionary timeframe. (Lemaux, 2009)" Is the Loss of Honeybees Due to Genetically Engineered Crops? No. Colony Collapse Disorder is not due to GE crops, but may be related to exposure to pesticides and other stresses, or lack of genetic diversity in honeybees. In Hawaii, introductions of varroa mites and small hive beetles are responsible for declines in honeybees. "In 2008 a meta-analysis of 25 independent studies assessing effects of Bt Cry proteins on honeybee survival (mortality) showed that Bt proteins used in commercialized GE crops to control lepidopteran and coleopteran pests do not negatively impact the survival of honeybee larvae or adults. Thus there are no data in the scientific literature supporting direct or indirect damage to bees caused by currently approved GEcrops engineered to make Bt proteins. (Lemaux, 2009)" Could Accidental Movement of Transgenes Occur From Genetically Engineered Crops to Wild Relatives or Non-Genetically Engineered Varieties? Perhaps. Gene flow from GE crops to wild relatives or non-GE crops can occur, but it depends on the crop species. In the case of commercially grown GE `Rainbow' papaya, self-pollination occurs, reducing the likelihood to practically nil of accidental movement of transgenes to a non-GE self-pollinating variety. "Pollen drift is a major, although not the only, conduit through which unwanted genes end up in crops..."gene flow is not limited to GE varieties and its impact is dependent on the trait, not the means by which the gene was created. (Lemaux, 2009)" 3 "Very low pollen drift (0.8%) was detected in fruit of`Kapoho' trees in the border row of one plantation when 90 embryos were assayed per fruit, while no pollen drift was detected in four other commercial plantings in which eight embryos were tested per fruit. (Gonsalves and others, 2012)." "Generalizations about whether gene flow presents significant economic or environmental risks cannot be made for either conventionally bred or GE crops; case-by-case evaluation is required. Many major agricultural crops are sexually compatible with wild and/or weedy relatives, and, if the plants grow in overlapping regions, crop-to-weed or crop-to-wild relative gene flow could result. This outcrossing to wild populations can result in new combinations of genes that can improve, harm, or have no effect on the fitness of recipient plants. (Lemaux, 2009)" Have Transgenes moved from GE corn to Wild Relatives in Mexico? Perhaps; there are conflicting reports. A more important question is whether this accidental movement of transgenes has affected growth and fitness of Mexican corn? And there is no scientific evidence to answer that question yet. Quist (2001) showed that locally produced corn in Oaxaca, Mexico contained DNA segments used in GE maize to promote gene expression. However, GM crops are not approved for commercial production in Mexico. It's possible that local farmers planted seed from GM crops imported from the United States and then pollen flow moved the transgenes to locally grown corn varieties. (Gilbert, 2013) Later researchers did not find evidence of transgene flow in corn from Oaxaca, Mexico and Quist's (2001) study was criticized for technical deficiencies. Then, in 2009, Pineyro-Nelson and others (2009) found the same transgenes as Quist from samples taken in Oaxaca and across Mexico. (Gilbert, 2013) What Happens When Pollen Moves from Genetically Engineered Crops to Organic Crops? Accidental movement of transgenes from GE crops to organic crops will not result in loss of accreditation. Use of GE crop varieties in certified organic farming is specifically prohibited. "The presence of detectable levels of GE material in a crop does not constitute a violation of National Organic Program (NOP) regulations nor is it reason to lose accreditation, as long as the grower has not intentionally planted GE seed and has taken reasonable steps to avoid cross pollination....The USDA-NOP [National Organic Program] informed state agricultural departments that up to 2005 no organic farmer had lost organic certification because of AP of GE material. (Lemaux, 2009)" "Some consumers, however, expect foods labeled as organic not to contain GE ingredients and have zero tolerance for their presence. Achieving 100% purity for any agricultural commodity is a practical impossibility given the nature of our food system, the reproductive biology of plants, and the highly sensitive detection methods available to identify GE traits (Lemaux, 2009). 4 Are Indian Farmers Committing Suicide due to GE crops? No, this is a false claim by environmental activist Vandana Shiva. "During an interview in March, Vandana Shiva, an environmental and feminist activist from India, repeated an alarming statistic: "270,000 Indian farmers have committed suicide since Monsanto entered the Indian seed market," she said. "It's a genocide." (Gilbert, 2013)" Researchers at the International Food Policy Research Institute in Washington DC showed that Ms. Shiva's claim is false, because the number of suicides among farmers between 1997 to 2007 did not change from around 20,000 per year over this 10-year period. (Gilbert, 2013) Can Organic, Conventional and Genetically Engineered Cropping Systems Coexist? Yes, organic, conventional, and GE cropping systems can co-exist, provided that strategies are developed to allow ALL neighbors to farm in an economically viable way. "Thus, coexistence strategies must be devised to allow both neighbors to farm in an economically viable manner." These strategies could include buffer areas (Lemaux, 2009). "One factor hampering coexistence is the demand for zero tolerance for GE presence. Achieving 100% purity with any biological system is impossible and would require a complete ban on growing GE crops. (Lemaux, 2009)" Can Use of Genetically Engineered Crops or Organic Farming Lead to More Sustainable Agricultural Production Systems? Yes, GE plants can contribute towards a more sustainable agriculture. "Sustainability has no single meaning, but one accepted definition is to meet the basic needs of today's inhabitants while preserving resources to enable future generations to flourish. (Lemaux, 2009)" GE plants have the potential to: a) increase water use and fertilizer efficiencies; b) remediate soil contaminants; c) increase no-till or low-till practices; d) to help reduce greenhouse gases; and e) produce higher yields without increasing land usage, particularly in developing countries. (Lemaux, 2009) References: Lemaux, P. 2009. Genetically engineered plants and foods: A Scientist's analysis of the issues (Part II). Annu. Rev. Plant Biol. 60:511-559. Gilbert, N. 2013. Case Studies: A hard look at GM crops. Nature. 497:24-26. http://www.nature.com/news/case-studies-a-hard-look-at-gm-crops-1.12907 Gonsalves, D., C. Gonsalves, J. Carr, S. Tripathi, T. Matsumoto, J. Suzuki, S. Ferreira, and K. Pitz. Assaying for pollen drift from transgenic `Rainbow' to nontransgenic `Kapoho' papaya under commercial and experimental field conditions in Hawaii. Trop. Plant Biol. 5:153-160. 5 Pineyro-Nelson, A. and others. 2009. Mol. Ecol. 18:750-761. Quist, D. and I.H. Chapela. 2001. Nature. 414:541-543. 6 Exploring Coexistence: Preliminary Best Management Practices for Diverse Farming Practices Report to the Hawaii Department of Agriculture Submitted by Hawaii Farm Bureau Federation December 2006 Executive Summary The Hawaii Farm Bureau Federation sponsored and hosted the Coexistence of Farming Practices meetings, as mandated by the 2005 Hawaii State Legislature (Appendix 1). The purpose of the meetings was to initiate discussions and identify common ground among farmers in Hawaii who use conventional, organic, and biotech farming practices. A diverse range of agricultural producers took part in these discussions, some of who practice more than one method on their respective farms. Participants engaged in a seven-meeting process in which they shared their practices and learned about the regulations that affect agriculture. Participating farmers worked together to create recommendations for best management practices (BMPs) on how to farm using their method of choice without impeding the agricultural practices and business of other farmers. The results of these discussions are detailed in this report. The participants identified and categorized BMPs into three subject areas: Seed Supply, Biological Drift Management and Chemical Contamination. A general structure was developed within each of these areas, covering communication, education and governance, as well as practices unique to each topic. Improved Communication • Communication between stakeholders is critical. • Farmers can alleviate some problems by discussing agricultural practices with neighbors. • If voluntary neighbor communications are not effective, then reporting agricultural practices to a third-party governing body will be necessary. The third-party body may make information about these practices widely available. Improved Education • Good education about agricultural BMPs is essential. • The educational needs of farmers vary greatly based on crop and operation size. • Without education, liability for misconduct in agricultural production is a significant concern that exacerbates potential disagreements among neighbors. • Education must also include consumers and the general public. Third-Party Governance • Best management practices will only improve the agricultural industry if they are enforced. A third-party body should be employed to encourage effective communications, supply education, and mediate compliance with best management practices. The recommended best management practices were agreed to by all participants. Participants were also given the opportunity to submit alternative BMPs if they felt their views were not adequately represented by a recommended BMP. Alternative BMPs were not discussed by or agreed to by the group. 2 Hawaii Farm Bureau Federation firmly believes that farmers must work together on issues critical to the agriculture industry. The development of these recommended best management practices is a first step in an ongoing dialogue about managing vital resources with wisdom, respect for one another and commitment to future generations. 3 Umbrella Statement The participants adopted a broad statement of purpose illustrating the goals they set to achieve in this project. We, the united farmers of Hawaii, understand that agriculture is not just a career path; it is a necessity to humanity's existence and evolution. In this spirit,we have come together to consider the status of local agriculture in the context of current global circumstances. Our intention is to make a statement of commitment to pono, responsible agricultural practices that are aligned and in harmony with the needs and desires of our varied individual farmers, humankind and the environment that sustains us all. To that end, the true and lasting success for a farmer and his community begins with responsible stewardship and respect for the land; the aina. Our commitment to responsible respect for each other and the land will result in clean water, clean air,viable soil and environmental health while providing healthy, nutritious food. Through our ecological sensitivity and mutual respect will grow sustainable, economic success for individual farmers and health for our communities and state now and into the future. Agricultural collaboration starts with us,but ends with humanity. Framework for the Best Management Practices (BMPs) After significant discussion, the group agreed on a framework to guide the development of best management practices. The framework includes: • The achievement of a balance wherein farmers may engage in any farming practice or farming culture with minimum incursion, influence or detriment to and from other farming practices; • The establishment and continuation of a methodology for addressing new issues and solutions in order to maintain this balance; • The recognition that all farmers of all farming cultures require and deserve equal opportunity to technology, legislation, education and funding that enhances their economic stability; and • That State institutions understand and recognize the need for equal opportunity of all farming cultures in their deliberations, procedures and enactments. 4 Best Management Practices Topic 01: Seed Supply Rationale General crop production practices for all seed crops -- including the growing, harvesting, processing, transport and use of storage equipment-- are possible points of seed contamination or co-mingling. All seed producers need to practice good crop husbandry, follow strict cleaning procedures, and maintain accurate records to avoid inadvertent contamination or co-mingling of seed crops. Maintaining high levels of seed varietal purity and biodiversity is vital as many sources of seed have diminished over the years. Identifying BMPs for preserving the integrity of these seed banks and germplasm repositories is important for all growers. Varietal integrity is essential to marketing and industry expansion. New, unique varieties appeal to consumers who might not have appreciated a crop before, thereby expanding the market. Variety selection is essential to ensure suitability of various crops to Hawaii's different microclimates and soil conditions. Well adapted varieties lead to better food security. Farmers need increased availability for distinct varieties obtained from seed producers and from careful and thoughtful on-farm seed selection. Farmers need best management practices that ensure new plantings will be of the intended variety through knowledge of genetics and pollen flow in their neighborhood. Food producers in Hawaii include the whole range between commercial agricultural producers and subsistence farmers. Farmers have a traditional right to save and collect nonpatented seed from their growing environment. In this way, crop seeds or plants available in the farmers' growing regions are included in their seed supply. Farmers can engage in plant and seed selection as appropriate to their crop and region. The group continues to grapple with questions about where the responsibility and resources for preserving seed purity rest. For example, local seed stock that remains free of unintended patented or foreign genes is a challenging issue. At the same time,plant breeders have the legal right to create and sell patented seed. There also continues to be challenging issues in the area of defining seed purity. The group discussed recommendations for supporting the integrity of existing, locally adapted seed stock. We support efforts by all parties to ensure that locally available seed stock remains pure. Many group members defined purity as that which is a reasonable goal in an agricultural seed production environment, recognizing that 100% purity, or"zero" presence of any unintended, unspecified, or non-targeted material, is scientifically impossible. However, other group members recognize that both certification and market requirements affecting organic and other international markets demand zero tolerance, thereby creating the potential for economic and market losses. 5 01.01 Seed Supply—Governance Form a review board of stakeholders with equal representation by conventional, organic and biotech farmers. The review board will meet quarterly or as necessary to: • Develop seed production protocols to protect important Hawaii crops (i.e. coffee, banana, etc.). • Track trends and issues in conventional, organic and biotech crop developments and regulatory changes that may impact Hawaii growers' efforts to maintain seed purity protection practices. • Review crops to provide data, information, agricultural practices and market concerns for the Hawaii Department of Agriculture (HDOA) to consider in developing Hawaii performance standards for future biotechnology permits. • Mediate and recommend solutions between growers prior to planting sexually compatible crops. 01.02 Seed Supply—Information Access The Hawaii Department of Agriculture currently hosts a biotech information portal with links to all sides of the issue that can provide information for grower discussions. 01.03 Seed Supply - Communication Prior to planting a crop of the same species or a crop that is sexually compatible, growers should inform and consult with neighboring growers and commodity groups within the pollen and seed transfer ranges. 01.04 Seed Supply—Separation Practices All seed producers must separate conventional, organic and biotech crops at all known points of possible co-mingling (see appendix 2 for table of Points of Vulnerability in the Seed Production Process), and monitor field workers as possible pollen and seed transporters. 01.05 Seed Supply—Advocacy Advocate for resources dedicated to research on organic methodology and on seed production that promotes organic and conventional breeding of seed. 6 Page 1 of 1 Murashige, Laura From: Jason Moniz [jasonmoniz73 @gmail.com] Sent: Monday, July 01, 2013 8:00 AM To: counciltestimony @co.hawaii.hi.us Subject: Testimony bill 79 Attachments: July 2 Testimony Bill 79 Jason Moniz.docx Please accept my written testimony in opposition of Bill 79. JASON D. MONIZ, D.V.M. (808) 960-8409 7/1/2013 My name is Jason Moniz, I'm president of the 42 member Hamakua Farm Bureau, a beef cattle rancher, member of the Hawaii Cattlemen' s Council and a veterinarian who has worked with livestock producers for the past 32 years . I continue to be strongly opposed to Bill 79 . My position has not changed as Bill 79 as amended continues to state that GM crops threaten our agricultural heritage, our environment and our public health. Council members, we are multigenerational farmers and ranchers of Hawaii and we are Hawaii' s agriculture heritage . We care for the environment we farm and ranch in and we strive every day to produce safe wholesome food. As advancements in technology are made and are approved by the USDA, FDA and EPA for all American Farmers, we expect to have the same rights as other farmers and ranchers elsewhere in the State and the US . Bill 79 proposes to take those rights away from us . Specific issues I have with Bill 79 are : 1 . Bill 79 continues to claim transgenic crops as harmful to health and the environment . 2 . Bill 79 prohibits the current and future production and use of certain deregulated crops which are available to other farmers and livestock producers throughout the US and State of Hawaii . 3 . Bill 79 adds significant regulation, financial burden, requires signage that taints, stigmatizes and targets users for protest and agroterroism. 4 . Bill 79 proposes draconian enforcement and promotes litigation towards farmers and the County. One third of the States agriculture farm gate value is produced in Hawaii County. Thirteen percent (13%) of that production comes from organic farmed products, coffee and taro which are required to or have chosen to produce GMO free. That is their requirement or choice and we respect that . Nothing we argue for or against with this Bill threatens to change that . Livestock, aquaculture, flowers, banana and papaya combined account for 63% of the County' s farm gate value . You have heard from all of us that the continued use of transgenic tools and feed is critical for production of our commodities . You have also heard that it is very important that transgenic technology Seed Supply Alternative#1 Rationale Coexistence between genetically modified organisms (GMO) and non-GMO crops is not biologically possible. While seed producers can attempt to avoid inadvertent contamination of their seed crops, it has proven impossible to keep contamination from occurring in the agricultural communities. Of the major deregulated GMO crops in the United States (corn, soy, cotton and canola), all have shown contamination, or adventitious presence, in the seed supply of conventional and organic counterparts. In August 2006, in the midwestern US, long grain rice crops were shown to be contaminated with a GMO rice, LLRICE601. This rice was not deregulated by the USDA until November 24, 2006. This rice was never planted commercially, yet the contamination was widespread. The USDA's actions on this incident were unprecedented. They have implemented "approval by contamination", an after-the-fact approval. Due to lost markets, rice farmers in six states have filed class action lawsuits against Bayer Crop Science, the developer and patent holder of LLRICE601. 01.01 Seed Supply - Governance Form a review board of stakeholders with equal representation by organic, conventional, and biotech farmers. Also included will be the Department of Health and an ecologist. The review board will meet quarterly or as necessary to: • Make recommendations to the HDOA on introductions of new GMO agricultural crops in the State of Hawaii. This would include the possibility of prohibiting the planting of certain crops in order to protect Hawaii food crops that are at risk of contamination. The prohibition would also include field trials of these important crops. (See above paragraph describing rice contamination which most likely occurred from field trials.) • Work with growers organizations to achieve consensus on whether to introduce a new GMO crop into our Hawaiian growing environment. • Make available to farmers information from around the globe on GMO contamination, market loss, testing costs, loss of seed lines, and loss of choice when their industry is considering an introduction of a GMO crop into our state. 01.03 Seed Supply—Communication As pollen and seeds are unable to follow communication guidelines, and farmers cannot completely control them, the best practice to prevent unintended GMO contamination is to not plant any GMO versions of agricultural crops in our islands. It is not sound science to expect farmer—to-farmer discussions to prevent pollen flow, and due to the normal constraints of farming(weather, labor and timing), it is not always possible to have these important discussions. 7 01.04 Seed Supply— Separation Practices • As the recent examples of the unintended GMO contamination of long rice and bent grass have shown, separation practices cannot prevent gene flow. The best practice to prevent seeds of important Hawaii crops from being contaminated is to not grow GMO crops outside of the greenhouse. • All growers of GMO crops must notify conventional and organic producers in their area of intent to grow these crops, possibly through their local cooperative extension agents. 8 Seed Supply Alternative #2 01.01 Seed Supply—Governance A coexistence advisory panel with equal representation by conventional, organic and biotech farmers and a trained USDA certified mediator should be established. The advisory panel may meet quarterly or as necessary to: • Develop commercial or professional seed production guidelines and recommendations to protect important Hawaii crops (i.e. coffee, banana, etc.). • Track trends and issues in conventional, organic and biotech crop developments and regulatory changes that may impact Hawaii growers' efforts to maintain seed purity protection practices. • The coexistence panel may choose to work with or partner with commodity groups or professional trade associations to further develop and explore these and future BMPs. • This coexistence advisory panel should be tasked with facilitating better education and communication between commercial and professional growers. 01.02 Seed Supply—Information Access The HDOA is encouraged to provide increased education and assistance to interested parties seeking information regarding access to all seed sources. 01.03 Seed Supply—Communication Prior to planting a sexually compatible crop, growers should make every effort to inform and consult with neighboring growers and commodity groups in an effort to minimize potential biological drift. 01.04 Seed Supply—Separation Practices All seed producers are encouraged to separate conventional, organic and biotech crops at all known points of possible seed co-mingling or pollen movement. 01.05 Seed Supply—Advocacy Not relevant to Best Management Practices. 9 Topic 02: Biological Drift Management Rationale The group determined that there are three main biological drift categories: biological drift associated with pollen, pathogens and insects. Pollen drift is a biological issue when sexually compatible species with divergent genetic backgrounds are planted in a proximity that makes their unintended mating a possibility. An important example in Hawaii would be between genetically modified (GM) and non- GM crops like papaya and corn. There are also other pollen drift issues exclusive of GM crops associated with seed and crop purity. The other biological drift categories include pathogen and insect drift. This could be an issue between neighboring farmers when pathogens or insects from a farmer's crop also impact their neighbors in a negative manner. In an effort to alleviate the current issues associated with biological drift, it is recommended that farmers use measures to enable them to use the cultivation method of their choice without impacting their neighbors. These measures should be robust and broad enough to handle future issues that may develop in the agricultural sector of Hawaii. The following recommendations are just a starting point. The committee believes that there are specific areas that need to be addressed on a crop-by-crop basis by appropriate experts from the agricultural community in Hawaii to establish a set of standards for each crop and a long-term environment for coexistence. Specific issues to address: 1. Pollen: GMO and non-GMO crops 2. Pollen, Pathogen, Insect: seed/crop purity 3. Pollen, Pathogen, Insect: Hawaii-specific environment/wind 4. Pollen, Pathogen, Insect: Insect pollinators, and byproducts like honey 5. Address the changing landscape of agriculture in Hawaii over time: water/land/resources 6. Other issues may be identified in future conversations. 02.01 Biological Drift—Communication Communication between stakeholders is critical. We recommend that neighboring farmers communicate with each other about their cultivation methods and crops so that any potential issues can be addressed before they become a problem. If for some reason this is not possible, perhaps a third part organization (like the Hawaii Farm Bureau Federation) could facilitate communications. These 10 communications are critical to the development of appropriate measures to ensure the needs of each farmer. 02.02 Biological Drift- Development of Appropriate Separation Schemes Crops may be separated to prevent cross-pollination. These separation schemes are based on the biology of each crop, and include scientifically determined separation distances, planting sexually compatible species at different times (temporal separation), and using crop-specific methods to control flowering and pollen release. Farmers can work with university researchers and other experts to develop crop-specific needs to address on-farm issues. This BMP applies to large and small-scale farms (inclusive of community and urban garden centers), and ultimately enables farmers to produce marketable crops. 02.03 Biological Drift- Agricultural Practices Farmers should be aware of agricultural practices that prevent cross- contamination. In addition to the separation schemes described in Section 02.02, education should be provided to ensure that farmers are aware of specific needs to control volunteers and other post-harvest measures that are required for their production methods. Farmers should also use integrated pest management(IPM) methodologies within all farming methods to control negative and positive insect populations. Farmers should also practice good agricultural methods to minimize weeds so that pathogens and insects do not prosper in surrounding non-cropping areas. 02.04 Biological Drift—Governance Should issues arise between farmers, a"CoExistence Board" made up of experts from the University of Hawaii, HDOA, USDA, and EPA should be formed to govern over disagreements. Organic, conventional and biotech farmers would serve on this board to deal with issues that have no other means of solution. 11 Biological Drift Management Alternative#1 Rationale USDA APHIS recognizes, and has expressed numerous times, that deregulated (legal to plant) GMO crops will eventually cross-contaminate their conventional and organic counterparts. They are not concerned with the development of appropriate separation schemes for deregulated crops. To most organic and conventional farmers, this is not seen as regulation or protection of their crops. It is questionable whether it is possible for the Hawaii Farm Bureau Federation to do an objective job of facilitating and preparing any communication as it is constrained by its membership in the American Farm Bureau Federation. AFBF sets strong guidelines for their member states. In 2002, the Kona County chapter of the Farm Bureau, in their solidarity with the Kona Coffee industry, tried to support a moratorium on GMO coffee in Hawaii County and was forced to withdraw its support, as it was not in line with national guidelines. 02.01 Biological Drift- Communication Facilitation of communication will not control the movement of pollen and seeds in our agricultural environment. It is not sound science to expect farmer-to- farmer discussions to prevent pollen flow. The best practice to prevent transgenes from drifting is to not plant them in our islands until it can be proven that the inevitable contamination will cause no economic, environmental or health harm. 02.02 Biological Drift—Development of Appropriate Separation Schemes The HDOA withhold concurrency on field trials or notifications of any crop that can cross with an existing agricultural industry or food crop in Hawaii. This will prevent accidental contamination from occurring. 02.03 Biological Drift—Agricultural Practices Farmers must be educated about the risks and benefits of planting GMO crops in Hawaii. 02.04 Biological Drift—Governance Create a statewide roundtable of stakeholders which would include GMO, conventional and organic farmers, a representative from the Department of Health, an ecologist, a representative from the Agriculture and Environment committees of both the Hawaii State House and Senate, and a representative from the Environmental Center of the University of Hawaii at Manoa. 12 This roundtable would look at: 1. An analysis of the health, environmental, economic and cultural risks and benefits associated with the growing of GMO and non-GMO agricultural crops in the state. 2. How the State can protect farmers who choose not to grow GMO crops. 3. Create a working plan to protect the seed supply of conventional, organic and GMO farmers and home gardeners. This will contribute to Hawaii's food security and future agriculture sustainability. 13 Biological Drift Management Alternative#2 02.01 Biological Drift—Communication Communication between stakeholders is critical. It is recommended that neighboring farmers communicate with each other about their cultivation methods, utilization of BMPs and crops so that any potential issues can be addressed. If for some reason this is not possible, perhaps a third party organization (like the Hawaii Farm Bureau Federation) or the USDA certified mediation board could facilitate communications. This panel believes communication is a critical component to ensure successful coexistence among Hawaii's diverse agricultural sectors. 02.02 Biological Drift—Development of Appropriate Separation Schemes Crops may be separated to prevent cross-pollination. Separation of crops is routinely based on the biology of each crop, and traditionally includes scientifically determined (geographic isolation) separation distances, planting sexually compatible species at different times (temporal separation), and the use of other crop-specific methods to control flowering and pollen release. Commercial and professional farmers, or farm managers, are encouraged work with credible and identifiable experts and other resources (i.e., university researchers and other experts)to develop crop-specific recommendations and guidelines that address on-farm issues. The coexistence advisory panel, or similar entity as previously proposed and discussed, in conjunction with organizations such as the University of Hawaii CTAHR and the Hawaii Farm Bureau Federation is encouraged to identify and make available to both public and private interests, "links" or contact information to organizations, and other resources that may provide additional guidance in these areas. 02.03 Biological Drift—Agricultural Practices Farmers should be aware of agricultural practices that prevent unintended pollen movement. This panel recommends increased education and resources be provided by the HDOA, UH CTAHR and other appropriate resources so that professional and commercial farmers and/or farm operators are better aware of specific tools and options that best manage, and/or minimize potential for unintended pollen movement. Farmers are encouraged to use integrated pest management (1PM) methodologies, including judicious use of chemicals, within all farming methods to control negative and positive weed and insect populations. Farmers should also practice good agricultural methods to minimize weeds so that pathogens and insects do not prosper in surrounding non-cropping areas. 14 02.04 Biological Drift—Governance Unresolved conflicts or concerns among professional and/or commercial farmers and farm operators may be brought before the coexistence panel, or appropriate other entities, for further mediated discussion. This conflict-resolution process shall be limited to matters where economic interests are quantifiable and/or concerned. 15 Topic 03: Chemical Contamination Rationale The use of agricultural chemicals should be incorporated with other sound management practices. Farmers should choose methods that will manage pests (insects, weeds, plant diseases and vertebrates) cost-effectively while causing the least possible harm to people and the environment. Accurate pest identification and knowledge of biological developmental processes and behaviors are critical to effective control. To control pests with chemicals, users are required by law to comply with all the instructions and directions supplied by the manufacturer. A primary aim of applicators of agricultural chemicals should be to minimize the possibility of spray drift as much as possible, and to apply the chemicals in the most efficient and effective manner. Both of these aims are met when applicators use principles of`good agricultural practice' to maximize the amount of chemical reaching the target (intended site of application) and to minimize the amount of chemical being wasted on `non-target' sites. For assistance in developing a Chemical Contamination BMP contact your local CTAHR Extension Agent, USDA/NRCS, or the HDOA. The application of chemical pesticides and fertilizers can spread (by air and in ground water) past the targeted area into neighboring areas. Excessive or unintended application of chemicals can cause harm to people, animals, beneficial insects and the environment. In order to minimize risk to others, farmers who use chemical pesticides and fertilizers should (1) communicate with their neighbors, (2) accurately map their farms, (3) use integrated pest management (IPM) methodologies and follow approved methods of chemical application, and (4) endure the consequences of not following the above guidelines. The main chemical contamination issues addressed in this BMP are chemical drift(by air) and runoff mitigation (in ground water). 03.01 Chemical Drift 03.01.01 Chemical Drift—Communication Farmers should agree upon a chemical application schedule with their neighbors. In the event that first-party communication with neighbors is not effective, farmers may need to report their chemical application schedules with a third-party governing agency, such as the EPA or the DOA pesticide branch. Farmers who do not communicate chemical application schedules with neighbors or a governing agency, and cause chemical disturbance to neighbors, may be liable for damages (see 03.01.04—Liability and Consequences). 16 03.01.02 Chemical Drift—Farm Mapping Accidental chemical drift can be avoided with knowledge of the areas surrounding the farm. Farmers should identify their property boundaries (e.g. crop fields, orchards, pastures, buildings, roads, uncultivated areas, windbreaks, hedgerows, ponds, streams, drainage ditches, dirt roads, and paved areas). Farmers should identify sensitive areas (e.g. houses, schools, wildlife, sensitive crops, etc) surrounding their property, and avoid chemical application where drift into these sensitive areas can occur. 03.01.03 Chemical Drift -Integrated Pest Management (IPM) and Chemical Application Controlling pests can be done by using IPM practices, a comprehensive approach to controlling insects, weeds, and plant pathogens. Windbreaks can be used around areas where chemicals are applied. A 300-foot buffer next to sensitive areas should be maintained. Farmers should properly calibrate chemical application equipment to avoid over-spraying. Farmers can also use low-drift nozzles and/or lower pressure on chemical spray equipment to limit drift. Farmers should also apply pesticide during light wind and lower temperatures, and avoid application when bees are pollinating to avoid accidental drift. 03.01.04 Chemical Contamination—Liability and Consequences In the event that farmers do not try (1) to communicate and agree upon an appropriate chemical application time with neighbors, (2) to identify and avoid chemical application around sensitive areas surrounding their property, and (3) to use agricultural practices to avoid excessive chemical application,they may be liable for chemical contamination of neighboring areas. Neighbors can initiate recourse by contacting the National Pesticide Information Center (NPIC) at 1- 800-858-7378 or http://npic.orst.edu. Organic growers can notify the HOFA Certification Coordinator or office as soon as the grower is aware of prohibited material drift onto certified acreage. 03.02 Runoff Mitigation 03.02.01 Runoff Mitigation—Communication Runoff can result in contamination of common water supplies, and can affect the quality of drinking water, well or rainwater catchments systems, septic tanks and cesspools, underground or above ground storage tanks (containing oil, diesel fuel, gasoline), stockpiles of 17 animal waste, storage of chemicals, and maintenance shops. Farmers should use Best Land Management Practices to minimize chemical runoff into common water supplies. Farmers should develop a pollution risk assessment plan for the following agricultural properties: land, nutrients, pests, irrigation, livestock and pastures. Farmers should also have a plan for the storage and disposal plan for chemicals and fuel. Farmers should work with the National Resource Conservation Service (NRCS), the Soil and Water Conservation District (SWCD), and the University of Hawaii CTAHR to develop a conservation plan that effectively protects the agricultural properties mentioned above. 03.02.02 Runoff Mitigation—Farm Mapping By mapping farm property, farmers can minimize applying chemicals that will affect neighboring areas by water runoff. Because water flows naturally from a higher area to lower-lying areas, mapping properties is essential to ensure that chemical application will not affect surrounding areas. 03.02.03 Runoff Mitigation—Integrated Pest Management (IPM) and Chemical Application Farmers can employ agricultural practices to reduce the need for chemical pesticides and fertilizers, and therefore minimize chemical runoff. Farmers can rotate crops, use no-till practices, use crop covers, and use soil analysis to maintain a balance of minerals and elements. Farmers can also use compost to increase organic matter in the soil to reduce soil compaction and leaching, and use contour strips and windbreaks as buffers. 03.02.04 Runoff Mitigation—Liability and Consequences Farmers who do not use the above methods to communicate with their neighbors, map their farms to avoid unnecessary or over-spraying that can spread to neighboring farms, and use integrated pest management to best control agricultural challenges may be liable for unintentional or irresponsible spread of chemicals to neighboring areas. Neighbors can initiate recourse as stated in 03.01.04. 18 Recommended Next Steps This committee believes continued discussion, education and partnership in developing recommendations, guidelines and BMPs are necessary to ensure successful diversity within Hawaii's professional and commercial agricultural community. It is further anticipated that these recommendations and agreed-upon principles also benefit many others who are not economically invested or dependent upon commercial crop production. Therefore, this committee recommends the following: • Continued support and investment in an ongoing coexistence committee, as defined and described previously, that is tasked with identifying areas of concern to professional agriculture farmers and farm operators, and issuing as guidelines and recommendations that may best maximize opportunity and benefit commercial growers, while minimizing potential conflict. • A committee begins negotiation with possible third-party resources (i.e., UH CTAHR, HDOA, HDOH, USDA, HOFA, HFBF) to implement agreed-upon recommendations. • Establish timetable, criteria and scope for continued agricultural industry discussion on next set of BMPs. Topics to include, but not be exclusive to: o Address farmer-to-citizen relations issue (community neighbors, not just farmer neighbors). o Address the issue of preserving the traditional seed supply. o Review prioritized list of topics for additional BMPs and develop resources and time-table to address them. o Evaluate impact of BMPs and lessons learned from application of BMPs to inform future practice. o Conduct a full and candid discussion about liability. o Provide significant educational opportunities for individual/backyard/home gardeners to become aware of variety preservation and chemical usage. o Seek understanding of the role, responsibilities and membership of the Institutional Biosafety Committee at UH Manoa as they pertain to agricultural concerns. o Continue to explore ways to utilize traditional local agricultural practices to inform the development of future BMPs. 19 Appendix 1 —Hawaii State Legislation THE SENATE 208 TWENTY-THIRD LEGISLATURE, S • C • R • N O ■ S.D. 1 2005 STATE OF HAWAII H.D. 1 SENATE CONCURRENT RESOLUTION urging the legislature and administration to support and encourage Hawaii ' s AGRICULTURal community' s efforts toward successful co- existence among its sectors and to recognize the economic, human, and environmental benefits of such co-existence in a diversified agriculture industry. WHEREAS, agriculture is Hawaii ' s second-largest export industry and one of the largest contributors to the State ' s economic health; and WHEREAS, the long-term prosperity of Hawaii ' s agricultural community depends significantly upon diversity in research, production, and farming practices; and WHEREAS, Hawaii ' s agriculture industry continues to evolve and expand, occupying vacant agricultural lands and providing employment in rural Hawaii; and 20 WHEREAS, having diversification in Hawaii ' s agriculture industry -- including organic, conventional, and biotech farming and agricultural research -- is generating significant opportunities for economic growth in both export and import markets; and WHEREAS, successful diversification mandates that farmers be given the opportunity to choose which farming practices will best ensure the most productive use of their resources to reach their target markets in accordance with their personal preferences; and WHEREAS, the long-term development of diversified, sustainable tropical and subtropical agriculture in Hawaii and elsewhere requires the continuing advancement of technological and scientific knowledge to achieve the best farming practices in all sectors of agriculture; and WHEREAS, such knowledge and cooperation within Hawaii ' s papaya industry resulted in an identity preservation protocol with the Department of Agriculture that allowed more than eight hundred acres of non-transgenic papaya to coexist next to transgenic papaya and to meet certification requirements in the Japanese marketplace; and WHEREAS, having public and private research, and the transfer of knowledge and technology in many new areas of agriculture, have and will continue to provide substantial benefits to human health and the environment and are therefore critical to the well being of Hawaii ' s people, as well as to billions of others in developing nations around the world; and WHEREAS, organizations such as the College of Tropical Agriculture and Human Resources of the University of Hawaii, the Hawaii Department of Agriculture, Hawaii Agriculture Research Center, Maui County Farm Bureau, Hawaii Crop Improvement Association, and genetically modified organism free, organic, and conventional farmers are seeking to establish a broad-based dialogue on agricultural biotech as a result of community interest in agricultural research; and WHEREAS, the benefits to the State ' s economy, human health, and environment derived from a diversified agriculture industry and knowledge-based agriculture research and 21 technologies are of interest to all Hawaii ' s people; now, therefore, BE IT RESOLVED by the Senate of the Twenty-third Legislature of the State of Hawaii, Regular Session of 2005, the House of Representatives concurring, that the Legislature: supports the agricultural community' s efforts to promote choice of farming methods, practices, and crops; recognizes the economic value to the State of a diversified agricultural industry supported by mutually supportive co- existence among its sectors; and appreciates the value and importance of agricultural research for the benefit not only of Hawaii ' s farming community, but to farmers and peoples around the world; and BE IT FURTHER RESOLVED that the Department of Agriculture and the various and diverse agricultural interests, parties, producers, and agricultural stakeholders in Hawaii are requested to establish a dialogue and process to develop a framework of successful co-existence, with the goal of mutual success and prosperity for agricultural producers including organic, conventional, and biotechnology; and BE IT FURTHER RESOLVED that this dialogue be founded in fact and demonstrable science and that it result in a report to the Legislature and appropriate agencies about best practices and management plans to ensure success and co-existence among Hawaii ' s diverse agricultural interests; and BE IT FURTHER RESOLVED that the agricultural community is strongly encouraged to participate in community dialogues and communicate with the greater community on issues relating to agriculture; and BE IT FURTHER RESOLVED that the Departments of Agriculture and Business, Economic Development, and Tourism and the College of Tropical Agriculture and Human Resources of the University of Hawaii, whenever possible, are requested to assist and facilitate this process; and BE IT FURTHER RESOLVED that the Hawaii Farm Bureau Federation is requested to bring the stakeholders together in a meaningful process toward co-existence and report its findings and recommendations, based upon its meetings with stakeholders, to the Department of Agriculture; and 22 BE IT FURTHER RESOLVED that, after the Hawaii Farm Bureau Federation reports its findings and recommendations, the Department of Agriculture is requested to hold a public meeting to allow the public an opportunity to comment on the findings and recommendations; and BE IT FURTHER RESOLVED that the Department of Agriculture is requested to report to the Legislature about best practices and management plans to ensure success and co- existence among Hawaii ' s diverse agricultural interests; and BE IT FURTHER RESOLVED that the Department of Agriculture is requested to report its findings and recommendations, including any proposed legislation, to the Legislature no later than twenty days prior to the convening of the Regular Session of 2006; and BE IT FURTHER RESOLVED that certified copies of this Concurrent Resolution be transmitted to the Governor, the Chairperson of the Board of Agriculture, the Director of Business, Economic Development, and Tourism, the Dean of the College of Tropical Agriculture and Human Resources of the University of Hawaii, the Hawaii Agriculture Research Center, the Hawaii Farm Bureau Federation, the Hawaii Organic Farmers Association, and the Hawaii Crop Improvement Association. Report Title : Diversified Ag Industry 23 Appendix 2 — Table 4-3 Points of Vulnerability in the Seed Production Process VARIETY DEVELOPMENT Discarding seed of varieties that are •Spraying Seed packaging and preparation not ❑ Field testing on land rented from ❑ Spillage productive farmers ❑ Seed mixing ❑ Seed may be mixed with other •Farmers could accidentally harvest ❑ Mislabeling of seed varieties test plots Planting breeding nursery ❑ Seed may accidentally grow •Seed may be spilled Maintaining crop (resulting ❑ Pollen movement ❑ Cultivating in pollen movement) ❑ Harvest ❑ Spraying TRANSFORMATION •Cleanout of machine used for Making controlled pollinations Bombardment harvesting ❑ Pollinations made by hand Regeneration •Disposal of harvested seed ❑ Pollinations made by wind Maturation ❑ Volunteer plants emerge the ❑ Pollen movement ❑ Pollen movement following year Harvesting breeding nursery ❑ Physical mixing Discarding seed of varieties that are ❑ Seed on plants not harvested BACKCROSSING not productive ❑ Disposal of unwanted grain Seed packaging and preparation ❑ Seed may be mixed with other ❑ Disposal of unwanted plants ❑ Spillage varieties ❑ Cleanout of machine used for ❑ Seed mixing ❑ Seed may accidentally grow gleaning field ❑ Mislabeling of seed (resulting ❑ Disposal of seed gleaned from Planting breeding nursery in pollen movement) field Maintaining crop BREEDER SEED PRODUCTION ❑ Spilled grain ❑ Cultivating Seed packaging and preparation ❑ Volunteer plants emerge in field ❑ Spraying Planting breeding nursery the Making controlled pollinations Maintaining crop following year ❑ Pollinations made by hand Making controlled pollinations Transporting grain to shelling facility ❑ Pollinations made by wind Harvesting breeding nursery Shelling/threshing and seed ❑ Pollen movement Transporting grain to shelling facility processing Harvesting breeding nursery Shelling/threshing ❑ Accidental mixing of seed ❑ Seed on plants not harvested Seed processing and conditioning ❑ Mixing during shelling ❑ Disposal of unwanted grain FOUNDATION SEED PRODUCTION ❑ Mislabeling of seed during seed ❑ Disposal of unwanted plants Seed packaging processing ❑ Cleanout of machine used for Seed planting ❑ Improper discarding of seed gleaning field Crop maintenance Field testing of new varieties ❑ Disposal of seed gleaned from Pollen movement ❑ Seed packaging and preparation field Harvest ❑ Planting field test ❑ Spilled grain Transportation ❑ Crop maintenance ❑ Volunteer plants emerge in field Drying •Cultivating the Shelling •Spraying following year Conditioning ❑ Field testing on land rented from Transporting grain to shelling facility Storage farmers Shelling/threshing and seed COMMERCIAL SEED PRODUCTION •Farmers could accidentally harvest processing Seed packaging test plots ❑ Accidental mixing of seed Seed planting •Seed may be spilled ❑ Mixing during shelling Crop maintenance ❑ Pollen movement ❑ Mislabeling of seed during seed Pollen movement ❑ Harvest processing Harvest •Cleanout of machine used for ❑ Improper discarding of seed Transportation harvesting Field testing new varieties Drying •Disposal of harvested seed ❑ Seed packaging and preparation Shelling ❑ Volunteer plants emerge the ❑ Planting field test Conditioning following year ❑ Crop maintenance Storage •Cultivating Source: Union of Concerned Scientists; www.ucsusa.orq/food and environment/genetic engineering/pharmaceutical-and-industrial- crops-a-growing-concern.html; c. December 15, 2005. 24 Appendix 3 - Meeting Synopsis Phase 1 - September 9, 2005, Plant Quarantine Station, Honolulu Farmers using organic, conventional, and biotech methods convened to share detailed information about each type of farming. The six specific topics discussed included (1) the definition of each of the three growing methods, (2) challenges of each method, (3) benefits of each method, (4) marketing and business challenges of each method, (5) marketing and business benefits of each method, and (6) marketing projections for each method. Each of the six conversations ended by identifying the common ground shared by farmers of all methods. Farmers were able to meet face-to-face and initiate a more trust-based working relationship. Phase 2 - October 27, 2005, College of Tropical Agriculture and Human Resources (CTAHR), University of Hawaii —Manoa (UHM), Honolulu Two speakers were invited to discuss the policies and regulations for biotech and organic farming methods. Dr. John Turner was the presenter on Biotechnology Risk Assessment and Regulations. He is the Director of the Policy Coordination Division, Biotechnology Regulatory Services, United States Department of Agriculture—Animal and Plant Health Inspection Services (APHIS), located in Riverdale, Maryland. Keith Jones was the presenter on Organic Policies and Regulations. He is the Director of Program Development, National Organic Program, United States Department of Agriculture, located in Washington, D.C. A third speaker, Albert Louie, was the presenter on topics that affect all farmers in Hawaii, Seed Certification and Food Safety. He is the Seed Certification Director and Food Safety Coordinator, Quality Assurance Division, Hawaii State Department of Agriculture. Phase 3 —January 20, 2006, Plant Quarantine Station, Honolulu Mae Nakahata, Vice-president of the Hawaii Farm Bureau Federation, was a presenter on the best management practices (BMPs) for the coexistence of agricultural practices incorporated in other states and nations. After Ms.Nakahata's presentation, the group discussed a working definition of "coexistence." While the group did not arrive at an agreement on a definition, they did agree on a framework for the design of the BMPs. This framework is represented in the body of the report. The group also discussed the criteria that would be used to create the BMPs. The group decided that each BMP should consider(in no specific order): 25 • the economic viability of fellow farmers • the safety and protection of the environment • the accountability of each farmer • the needs of the farmer • the needs of the community. The group identified the important farming topics that would be used to create BMPs, including: • Contamination • Varietal preservation • Varietal development • Crop-specific buffer zones • Disease control • Pest& weed control • Invasive species • Research • Education to consumers about Hawaii's diverse agriculture • Liability • Legislation • Legislative appropriations (funding for agriculture) • Regulations • Niche markets • Testing • Water quality • Marketing and Distribution • Neighbor Relations and Communications The group divided into smaller subgroups. Each subgroup would research and address one or more of the topics mentioned above. The first three groups include the Biological Drift Mitigation group (focusing on pollen, pathogen, and insect drift),the Seed Supply group (focusing on preserving pure seed supplies), and the Chemical Drift and Runoff Mitigation group (focusing on minimizing drift of chemical fertilizers and pesticides). Each group consisted of at least one farmer who used biotech, conventional, and organic practices. These subgroups would discuss their respective topics and report back on their BMP drafts at the next meeting. Phase 4—March 1, 2006, Plant Quarantine Station, Honolulu The group decided to state the following goal for the coexistence process: To define and promote agricultural practices that benefits our economy, environment and community while mitigating negative consequences for the same. Each of the three subgroups (Biological Drift Mitigation, Seed Supply, and Chemical Drift and Runoff Mitigation) reported back on the BMPs each group drafted since the 26 January 20th meeting. Each draft consisted of a rationale for why the BMP was needed and an outline of recommendations for each topic. The main topics of Biological drift, Seed Supply, and Chemical drift sometimes included more specific subcategories, including communication, cultural practices, separation schemes, and liability/governance. The group also refined the list of possible BMP topics and voted on which topics were most important to them. The group created the following prioritized BMP topic list: Prioritized BMP Topic List Priority Topic Votes 1 Invasive Species 11 2 Water 10 3 Land Availability/Management 6 Agricultural Regulations 4 Neighbor Relations 5 Diverse Variety Preservation & Development (Seed Bank) 5 Food Nutrition 4 6 Workforce Development & Access 3 Marketing HI's Agriculture (Consumer Education) 7 Product Distribution 2 Food Safety (Safe Processing Methods, Safe Production Methods, Market Demands, Self-Regulation) 8 Valuing Diversity and Growing Methods (Organic Market Increase) 2 9 Labeling & Point-of-Origin Issues 1 Legislative Appropriations for Agriculture 10 Food Security (Production of Enough Food within the State, Preserving 0 Integrity of Shipping Capsule) Certification (organic, testing, GMO, pesticides, HACCP) Finally, the group discussed some issues that were important to address in order to continue with the process. The group thought that voting may not be necessary. Instead, the group thought that for each BMP drafted, a minority report could be included that addressed opinions different from those defined in the BMP. Additionally, in the process of drafting the BMPs, participants thought that they may not have the expertise to finish the BMPs and that other professionals should be recruited to contribute crop-specific information. Also, this six-meeting process may not be enough to finish BMPs, but should be extended so that the conversation would be maintained as new issues arise in the future. 27 Phase 5 - June 20, 2006, College of Tropical Agriculture and Human Resources (CTAHR), University of Hawaii —Manoa (UHM), Honolulu Two speakers were invited to discuss the liability issues of biological drift, chemical drift, and seed supply purity. These two speakers were Joe Mendelson, Legal Director, Center of Food Safety, and Drew Kershen, Professor, Oklahoma University School of Law. The group continued to share and revise their BMP drafts for the remainder of the session. Phase 6—August 24, 2006, College of Tropical Agriculture and Human Resources (CTAHR), University of Hawaii —Manoa (UHM), Honolulu In this meeting, the participants worked on final revisions to the BMP drafts they had been working on in the previous months. The group completed Biological Drift Management and Chemical Contamination. Phase 7—December 4, 2006, Plant Quarantine Station, Honolulu The participants finalized worked on Seed Supply, the umbrella statement, next recommendations and the executive summary. 28 Appendix 4 - Participants Routh Bolomet Melanie Bondera Kimberly Clark Una Greenway Grant Hamachi Adolf Helm Ken Kamiya Paul Koehler Doug MacCluer Vince Mina Loren Mochida Myrone Murakami Dean Okimoto Roy Oyama Delan Perry Al Santoro Richard Speigel Sarah Styan Warren Watanabe 29 continue to be available in the future to fight new diseases in crops and livestock, feed livestock and for our floriculture industry to remain competitive . Please understand and respect our choice and needs also. We have all spent many hours of many days reviewing scientific literature and summaries on transgenic research, its effect on human health, animal health, agriculture and the environment . We have all also met personally and had discussions with GMO and other experts . The preponderance of evidence from the scientific community agrees with the federal regulatory agencies that once deregulated GMO crops, feed and food pose no more risk to human health, agriculture and the environment than non GMOs . Apparently Councilwoman Willie must not agree with that conclusion and Bill 79 continues to reflect that . I believe society' s food needs and the market place will drive where we are with GMOs in the next ten years . Without legitimate scientific evidence that GMOs cause harm, particularly those that have been deregulated, do not place Hawaii County farmers and ranchers in this unfair position which will cause many to fail . Do not pass Bill 79 . Do not place unwarranted additional regulations, stigmatize and prohibit the production and use of transgenic technology in Hawaii County when there is no scientific basis to do so. We believe all types of agriculture can coexist on the Big Island and we will commit to work with you to achieve this coexistence. Thank you for all the time you have spent listening to our concerns and thank you for taking my testimony today.