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<br /> Feuat Bio-Agricuiturnl Sxvicea Inc ~ 90Q-32B-976° ITi 1131/97 .:d:27 PPd 13/14 <br /> GHB. The amount required for a given level of effect will vary from person <br /> to person, and the dose-response curve is fairly steep. Overestimating the <br /> dose can have consequences ranging in seriousness from ruining you plans <br /> for the evening to waking up in the emergency ward as a result of panic on <br /> the part of concerned-but-uninformed friends or relatives. <br /> Once you have found the levels that give you the effects you desire, they <br /> will remain consistent. Tolerance to GHB does not develop. However, <br /> recent <br /> (not current) alcohol consumption may decrease the effect of a given dose <br /> of <br /> GHB [Fadda, 1989]. <br /> Most people find that a dose in the range of 0.75-1.5 grams is suitable for <br /> prosexual purposes, and that a quantity in the range of 2.5 grams is <br /> sufficient to force sleep. <br /> Some people think that GHB might lower potassium levels and should <br /> therefore <br /> be taken with potassium supplementation. Some research papers have <br /> identified such an effect, others have not. If you want to play it safe, <br /> take a potassium supplement equal to 10% of the GHB dose. <br /> This article is excerpted and adapted from a chapter of a forthcoming <br /> book, <br /> Better Sex Through Chemistry available from CERI and Smart Publications, <br /> PO <br /> Box 4667, Petaluma, CA 94955 (phone: 707-769-8078, fax: 707-769- <br /> 1062, <br /> CompuServe: 71221,1427). <br /> References: <br /> Artru AA, Steen PA and Michenfelder JD. gamma-Hydroxybutyrate: Cerebral <br /> Metabolic, Vascular, and Protective Effects. J Neurochemistry. 35(5): <br /> 1114-9, November 1980. <br /> Chin MY, Kreutzer RA and Dyer JE. Acute poisoning from gamma- <br /> hydroxybutyrate <br /> in California. West J Med (United States). 1 56(4): 380-4, April 1992. <br /> <br />