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Faust Bio-Agricultural 5srviceo lnc. ~80B-32B-9760 $1/31/97 62',21 PM p5/14 GHB induces "remarkable hypotonia" (muscle relaxation) [Vickers, 1969]. It is now gaining popularity in France and Italy as an aid to childbirth.HB causes "spectacular action on the dilation of the cervix," decreased anxiety, greater intensity and frequency of uterine contractions, increased sensitivity to oxytocic drugs (used to induce contractions), preservation of reflexes, a lack of respiratory depression in the fetus, and protection against fetal cardiac anoxia (especially in cases where the umbilical cord wraps around the fetus' neck) [Vlckers, 1969; Laborl>:, 1984]. GHB is completely metabolized into carbon dioxide and water, leaving absolutely no residue of toxic metabolites [Vickers, 1 969; Laborit, 1972]. Metabolism is so efficient that GHB can no longer be detected in urine four to five hours after it is taken by injection [Laborit, 1964]. GHB activates a metabolic process known as the "pentose pathway" which plays an important role in the synthesis of protein within the body [Laborit, 1972]. It also causes a "protein sparing" effect [Laborit, 1964] which reduces the rate at which the body breaks down its own proteins. These properties, along with GHB's effect on growth hormone, underlie its common use as an aid to muscle-building and fat loss. Anesthetic (large) doses of GHB are accompanied by a small increase in blood sugar levels, and a significant decrease in cholesterol. Respiration becomes slower and deeper. Blood pressure may rise or fall slightly, or remain stable, but a moderate bradycardia (slowing of the heart) is consistent [Vickers, 1969; Laborit, 1964]. A slight drop in body temperature also occurs [Laborit, 1964]. GHB also stimulates the release of acetylcholine in the brain [Gallimberti, 1989]. GHB and Sieep GHB has been called "almost an ideal sleep inducing substance" [Smart Drugs